A patient is being treated with isoniazid (INH), rifampin, and pyrazinamide in phase I of treatment for tuberculosis. The organism develops resistance to isoniazid. Which drug will the nurse anticipate the provider will order to replace the isoniazid?
Correct Answer: B
Rationale: Ethambutol replaces INH in phase I if resistance occurs; ciprofloxacin or kanamycin are less common first-line options. If there is bacterial resistance to isoniazid, the first phase may be changed to ethambutol, rifampin, and pyrazinamide.
Nokea