A patient is to receive medroxyprogesterone (Depo-Provera) 700 mg weekly, intramuscularly, as part of palliative therapy for endometrial cancer. The medication is available in vials of 400 mg/mL. Identify how many milliliters will the nurse draw up and administer with each injection. (record answer using one decimal place)
Correct Answer: 1.8 mL
Rationale: To calculate: 400 mg/1 mL = 700 mg/x mL. Cross-multiply: (400 * x) = (1 * 700); 400x = 700; x = 700/400 = 1.75 mL, rounded to 1.8 mL.
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A woman is preparing for a 10 hour trans-Pacific flight. She has been taking the SERM raloxifene for 6 months. The nurse will provide which instructions to this patient?
- A. She needs to stop taking the drug at least 72 hours before the trip.
- B. She must remember to take this drug with a full glass of water each morning.
- C. She will not take the drug while traveling on the plane.
- D. No change in how the drug is taken will be needed.
Correct Answer: A
Rationale: Raloxifene should be stopped 72 hours before prolonged immobility (e.g., long flights) to reduce the risk of thromboembolism. Continuing the drug during travel increases this risk.
A patient is being treated for secondary amenorrhea. The nurse expects which drug to be used to treat this problem?
- A. Methylergonovine
- B. Estradiol transdermal
- C. Raloxifene
- D. Medroxyprogesterone
Correct Answer: D
Rationale: Medroxyprogesterone, a progestin, is commonly used to treat secondary amenorrhea by inducing withdrawal bleeding. The other drugs are not indicated for this condition.
The nurse recognizes that the risk of osteoporosis is higher in an individual with which risk factor?
- A. Whites or Asians
- B. Blacks
- C. History of participation in active sports
- D. Obesity
Correct Answer: A
Rationale: White or Asian descent is a risk factor for postmenopausal osteoporosis due to genetic predisposition and lower bone density. Active sports and obesity may reduce risk, and Black individuals have lower risk.
The nurse is teaching a patient about the adverse effects of fertility drugs such as clomiphene. Which is a potential adverse effect of this drug?
- A. Headache
- B. Drowsiness
- C. Dysmenorrhea
- D. Hypertension
Correct Answer: A
Rationale: Clomiphene can cause headaches as a side effect, along with vomiting, restlessness, and urticaria. Drowsiness, dysmenorrhea, and hypertension are not typical adverse effects.
The nurse is administering oxytocin. Which situation is an indication for the use of oxytocin?
- A. Decreased fetal heart rate and movements
- B. Stimulation of contractions during labor
- C. Cervical ripening near term in pregnant patients
- D. To reverse premature onset of labor
Correct Answer: B
Rationale: Oxytocin is used to stimulate uterine contractions during labor to induce or augment labor. It is also used for cervical ripening, but not to reverse preterm labor or address fetal distress.
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