Nokea
A patient on imipenem/cilastatin is at risk for which adverse effect?
- A. Allergic reaction
- B. Seizures
- C. C. difficile infection
- D. All of the above
Correct Answer: D
Rationale: Imipenem/cilastatin can cause allergic reactions, seizures (neurotoxicity), and C. difficile infection, making all potential risks.
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This drug is a respiratory stimulant:
- A. Doxapram
- B. Promethazine
- C. Dornase α
- D. Oxygen
Correct Answer: A
Rationale: Doxapram stimulates breathing by acting on the respiratory center in the brainstem.
Which of the following drugs is used for the management of atropine intoxication?
- A. Physostigmine
- B. Neostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Physostigmine, a cholinesterase inhibitor, crosses the BBB to reverse atropine's central effects.
Which of the following is used for the treatment of primary hyperaldosteronism:
- A. Furosemide
- B. Hydrocortisone
- C. Spironolactone
- D. Dexamethasone
Correct Answer: C
Rationale: Spironolactone is an aldosterone antagonist, making it effective for treating primary hyperaldosteronism by blocking excess aldosterone effects.
Which of the following has a strong anti-inflammatory effect:
- A. Prednisolone
- B. Triamcinolone
- C. Dexamethasone
- D. Prednisone
Correct Answer: C
Rationale: Dexamethasone has a strong anti-inflammatory effect due to its high glucocorticoid potency.
What would be the best source of drug information for a nurse?
- A. Drug Facts and Comparisons
- B. A nurses drug guide
- C. A drug package insert
- D. The Physicians Drug Reference (PDR)
Correct Answer: B
Rationale: A nurses drug guide provides nursing implications and patient teaching points that are most useful to nurses in addition to need-to-know drug information in a very user friendly organizational style. Lippincotts Nursing Drug Guide (LNDG) has drug monographs organized alphabetically and includes nursing implications and patient teaching points. Numerous other drug handbooks are also on the market and readily available for nurses to use. Although other drug reference books such as Drug Facts and Comparisons, PDR, and drug package inserts can all provide essential drug information, they will not contain nursing implications and teaching points and can be more difficult to use than nurses drug guides.