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A patient presents with chest pain that worsens with inspiration and is relieved by sitting forward. There is also evidence of deep vein thrombosis (DVT) in the lower extremity. Which cardiovascular disorder is most likely responsible for these symptoms?

  • A. Stable angina
  • B. Pulmonary embolism
  • C. Pericarditis
  • D. Aortic dissection
Correct Answer: B

Rationale: The patient's presenting symptoms of chest pain worsened by inspiration and relieved by sitting forward, with associated DVT in the lower extremity, suggest a high likelihood of pulmonary embolism. Chest pain that worsens with inspiration due to pleuritic involvement is a classic symptom of pulmonary embolism. Additionally, the presence of DVT in the lower extremity represents a risk factor for the development of pulmonary embolism, as clots originating in the deep veins can travel to the pulmonary circulation to cause an obstruction. Patients with pulmonary embolism may also exhibit signs of right heart strain, such as tachycardia, tachypnea, and sometimes hemoptysis.