A patient presents with gradual-onset weakness, spasticity, hyperreflexia, and positive Babinski sign. Imaging reveals demyelinating plaques in the white matter of the brain and spinal cord. Which of the following neurological conditions is most likely responsible for these symptoms?
Correct Answer: B
Rationale: The symptoms described - gradual-onset weakness, spasticity, hyperreflexia, positive Babinski sign, and demyelinating plaques in the white matter of the brain and spinal cord - are indicative of multiple sclerosis (MS). MS is an autoimmune disease where the body's immune system attacks the myelin sheath, leading to the formation of plaques in the central nervous system. The characteristic symptoms of MS include weakness, spasticity (stiffness in muscles), hyperreflexia (exaggerated reflex responses), and positive Babinski sign (upward movement of the big toe). While ALS (Amyotrophic lateral sclerosis) presents with progressive muscle weakness and atrophy without sensory involvement and demyelinating plaques, Guillain-Barré syndrome (GBS) is typically an acute inflammatory demyelinating polyneuropathy affecting peripheral nerves rather than the central nervous system, and myast