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A patient presents with gross hematuria, flank pain, and a palpable abdominal mass. Imaging reveals a large heterogeneous renal mass with areas of necrosis and calcifications. Which of the following conditions is most likely?

  • A. Renal cell carcinoma
  • B. Renal cyst
  • C. Renal abscess
  • D. Renal angiomyolipoma
Correct Answer: A

Rationale: The clinical presentation of gross hematuria, flank pain, palpable abdominal mass, along with imaging findings of a large heterogeneous renal mass with necrosis and calcifications are highly suggestive of renal cell carcinoma (RCC). RCC is the most common type of kidney cancer in adults. The presence of necrosis and calcifications are characteristic features of RCC. Imaging modalities such as CT scans or MRI can confirm the diagnosis by showing the typical features of RCC, including a solid mass with areas of necrosis and calcifications. It is important to further evaluate this patient, likely with a biopsy, to confirm the diagnosis and determine the extent of the disease for appropriate management.