Nokea
A patient requires 1,000 mL of IV fluid to be infused over 10 hours with a drop factor of 20 gtt/mL. What is the flow rate in drops per minute?
- A. 33 gtt/min
- B. 50 gtt/min
- C. 67 gtt/min
- D. 100 gtt/min
Correct Answer: A
Rationale: Flow rate = (Volume Drop factor) ÷ Time in minutes = (1,000 mL 20 gtt/mL) ÷ (10 60) = 20,000 ÷ 600 = 33.33 gtt/min, rounded to 33 gtt/min.
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Release of the mineralcorticoids is stimulated with:
- A. Low concentration of \mathrm{Na}+ in the blood
- B. Hypokalemia
- C. Low concentration of angiotensin II in the blood
- D. Low concentration of \mathrm{Mg} 2+ in the blood
Correct Answer: A
Rationale: Low blood sodium stimulates aldosterone release via the renin-angiotensin system.
Which of the following drugs has been shown to restore corticosteroid responsiveness for Bronchial Asthma:
- A. Salbutamol
- B. Sodium cromoglycate
- C. Zifirlukast
- D. Montelukast
Correct Answer: D
Rationale: Montelukast, a leukotriene inhibitor, enhances corticosteroid efficacy in asthma.
A nurse is caring for a patient who has been receiving a drug by the intramuscular route but will receive the drug orally after discharge. How does the nurse explain the increased dosage prescribed for the oral dose?
- A. Passive diffusion
- B. Active transport
- C. Glomerular filtration
- D. First-pass effect
Correct Answer: D
Rationale: The first-pass effect involves drugs that are absorbed from the small intestine directly into the portal venous system, which delivers the drug molecules to the liver. After reaching the liver, enzymes break the drug into metabolites, which may become active or may be deactivated and readily excreted from the body. A large percentage of the oral dose is usually destroyed and never reaches tissues. Oral dosages account for the phenomenon to ensure an appropriate amount of the drug in the body to produce a therapeutic action. Passive diffusion is the major process through which drugs are absorbed into the body. Active transport is a process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney. Glomerular filtration is the passage of water and water-soluble components from the plasma into the renal tubule.
A 35-year-old male patient is admitted to the hospital with pneumonia. He was originally being treated at home, but became worse when he quit taking his medicine. What would be an appropriate nursing diagnosis for this patient?
- A. Deficient knowledge: monitoring temperature
- B. Noncompliance
- C. Risk for injury related to office visits
- D. Non-adherence: overuse
Correct Answer: B
Rationale: Noncompliance reflects the patient's failure to continue prescribed treatment, worsening his condition.
Which of the following beta-blockers also has additional alpha-blocking activity?
- A. Nadolol
- B. Pindolol
- C. Labetalol
- D. Esmolol
Correct Answer: C
Rationale: Labetalol has both beta and alpha-1 blocking activity, making it unique among beta-blockers.