Nokea
A patient who has recently come from an endemic area presents with elevated body temperature, headache, chills, malaise, that is with the symptoms which are typical for a common cold. What laboratory tests are necessary to confirm or to refute the diagnosis of malaria?
- A. Microscopy of blood smears
- B. Study of lymph node punctate
- C. Urinalysis
- D. Study of cerebrospinal fluid
Correct Answer: A
Rationale: The correct answer is A: Microscopy of blood smears. Malaria diagnosis is confirmed by identifying the Plasmodium parasite in a blood smear. This step is crucial as it directly visualizes the causative agent. The other choices are incorrect as they do not directly detect malaria parasites. B: Studying lymph node punctate is not specific for malaria. C: Urinalysis does not show malaria parasites. D: Studying cerebrospinal fluid is used to diagnose conditions affecting the brain and spinal cord, not malaria.
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Bacterial ribosomes consist mainly of:
- A. Carbohydrates
- B. Lipids
- C. DNA
- D. rRNA
Correct Answer: D
Rationale: The correct answer is D: rRNA. Bacterial ribosomes consist mainly of ribosomal RNA (rRNA), which plays a crucial role in protein synthesis. Ribosomes are composed of rRNA and proteins, with rRNA being the major component. rRNA serves as the structural and catalytic component of the ribosome, aiding in the binding of mRNA and tRNA during translation. Carbohydrates (A) and lipids (B) are not primary components of ribosomes, and DNA (C) is not found in ribosomes as they are involved in storing genetic information, not in protein synthesis.
On examination of a patient with disease onset 5 days ago the doctor suspected tularemia and prescribed the patient tularin intracutaneously. What is the purpose of this drug administration in the patient?
- A. Allergy diagnostics
- B. Prognosis for the disease
- C. Treatment
- D. Treatment evaluation
Correct Answer: C
Rationale: The correct answer is C: Treatment. Tularin is a specific immunizing agent used for the treatment of tularemia. The purpose of tularin administration in this patient is to provide a targeted treatment against the suspected tularemia infection. It helps the patient's immune system to recognize and fight against the bacteria causing the disease.
Explanation for other choices:
A: Allergy diagnostics - Tularin is not used for allergy diagnostics, as it is specifically indicated for tularemia treatment.
B: Prognosis for the disease - Tularin is not used to predict the outcome of the disease but rather to treat the infection.
D: Treatment evaluation - Tularin is not used for evaluating the effectiveness of treatment but for actively treating the tularemia infection.
Which organism is responsible for cholera?
- A. Salmonella typhi
- B. Vibrio cholerae
- C. Escherichia coli
- D. Shigella dysenteriae
Correct Answer: B
Rationale: The correct answer is B: Vibrio cholerae. Cholera is caused by this specific bacterium. Vibrio cholerae produces a toxin that leads to severe diarrhea and dehydration. Salmonella typhi causes typhoid fever, Escherichia coli can cause various infections but not cholera, and Shigella dysenteriae causes dysentery, not cholera. Therefore, the correct choice is B.
Which of the following infectious disease is considered a newly emerging disease?
- A. Hantavirus
- B. Malaria
- C. Tuberculosis
- D. Chlamydia
Correct Answer: A
Rationale: The correct answer is A: Hantavirus. Hantavirus is considered a newly emerging disease because it was first identified in the late 20th century. It is transmitted to humans through rodents and can lead to severe respiratory illness. Malaria, Tuberculosis, and Chlamydia are not considered newly emerging diseases as they have been known for centuries and continue to be prevalent worldwide. Therefore, based on the timeline of discovery and emergence, Hantavirus is the most recent infectious disease among the options provided.
An adult patient with type 2 diabetes attends the emergency room. He reported that two days ago he was accidentally injured in the left leg, but he did not seek medical care. At the time of examination, an infected wound was found, surrounded by a large area of inflammation with characteristic tissue crepitation on palpation and with foul odor. Blood (for hemoculture) and wound secretions were taken for microbiological testing. The microscopic examination reveals large Gram-positive bacteria, with centrally located spores. These bacteria were unable to grow in vitro at presence of oxygen. The most likely cause of this disease is:
- A. Clostridium tetani
- B. Clostridium perfringens
- C. Clostridium botulinum
- D. Clostridium difficile
Correct Answer: B
Rationale: The correct answer is B: Clostridium perfringens. In this case, the patient's presentation of infected wound with tissue crepitation, foul odor, and Gram-positive bacteria with centrally located spores that cannot grow in the presence of oxygen is indicative of gas gangrene caused by Clostridium perfringens. This anaerobic bacterium produces various toxins that lead to tissue destruction and gas production in the affected area. Clostridium tetani (choice A) causes tetanus, characterized by muscle stiffness and spasms. Clostridium botulinum (choice C) causes botulism, leading to muscle paralysis. Clostridium difficile (choice D) is associated with antibiotic-associated diarrhea. These choices are incorrect as they do not match the clinical presentation described in the question.