Foundations and Adult Health Nursing Test Bank Related

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A patient with a severe bacterial infection has elevated levels of C-reactive protein (CRP) in their blood. Which of the following functions does CRP primarily serve during the acute phase response?

  • A. Opsonization of pathogens
  • B. Activation of complement system
  • C. Phagocytosis of pathogens
  • D. Neutralization of toxins
Correct Answer: B

Rationale: During the acute phase response, C-reactive protein (CRP) primarily serves to activate the complement system. CRP binds to phosphocholine on the surface of pathogens, allowing for the activation of the classical pathway of the complement system. This leads to the recruitment of immune cells, opsonization of pathogens, and enhancement of phagocytosis. The activation of the complement system by CRP plays a crucial role in the host defense against infections, aiding in the elimination of pathogens and the resolution of inflammation.