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A patient with diarrhea had stool microscopy revealing flagellated protozoa with two nuclei. What is the most likely causative agent?

  • A. Giardia lamblia
  • B. Entamoeba histolytica
  • C. Trichomonas vaginalis
  • D. Balantidium coli
Correct Answer: A

Rationale: The correct answer is A: Giardia lamblia. Giardia lamblia is a flagellated protozoan with two nuclei, known as the "falling leaf" appearance. It causes diarrhea in humans through ingestion of contaminated water or food. Entamoeba histolytica causes amoebic dysentery, characterized by bloody diarrhea and colitis. Trichomonas vaginalis is a sexually transmitted protozoan causing vaginal discharge but is not found in stool. Balantidium coli is a ciliated protozoan causing diarrhea but does not have flagellated forms.