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A patient with suspected pulmonary embolism (PE) presents with sudden onset dyspnea, pleuritic chest pain, and hemoptysis. Which of the following diagnostic tests is most appropriate for confirming the diagnosis?
- A. Chest X-ray
- B. Electrocardiography (ECG)
- C. D-dimer assay
- D. Spiral computed tomography (CT) angiography
Correct Answer: D
Rationale: Spiral CT angiography is the most appropriate test for confirming the diagnosis of pulmonary embolism (PE) in a patient with suspected PE. It is a non-invasive imaging modality that can detect filling defects within the pulmonary vasculature indicative of a clot. This diagnostic test has high sensitivity and specificity for diagnosing PE, making it a valuable tool in the management of patients with suspected PE.
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A patient with a chronic viral infection demonstrates persistently elevated levels of CD8+ cytotoxic T cells in their blood. Which of the following mechanisms is most likely responsible for this observation?
- A. Activation-induced cell death (AICD)
- B. T cell exhaustion
- C. Thymic involution
- D. Antigenic variation
Correct Answer: B
Rationale: T cell exhaustion is a state of T cell dysfunction that arises during chronic viral infections or cancer. In the case of a chronic viral infection, the persistent exposure to viral antigens leads to continuous stimulation of CD8+ cytotoxic T cells. Over time, this sustained stimulation can lead to T cell exhaustion, characterized by the upregulation of inhibitory receptors, impaired effector functions, and reduced proliferative capacity. As a result, despite the elevated levels of CD8+ T cells in the blood, their function may be compromised, ultimately impacting the immune response against the viral infection. In contrast, activation-induced cell death (AICD) may contribute to T cell loss during chronic infections but would not explain the persistently elevated CD8+ T cell levels. Thymic involution refers to the age-related decline in thymus function, which is not directly related to the observed increase in CD8+ T cells. Antigenic
Her priority in managing community health needs is through knowing in-depth the PREVALENCE of diseases because it indicates the ______.
- A. risks to health problems
- B. Priority needs of the people.
- C. presence of health problems
- D. magnitude of health problems
Correct Answer: D
Rationale: Knowing the prevalence of diseases provides information on the magnitude of health problems within a community. Prevalence refers to the proportion of individuals in a population who have a particular disease or condition at a specific point in time. By understanding the prevalence rates of different diseases, healthcare providers can better assess the extent of health issues affecting the community. This information is crucial for prioritizing resources and interventions to address the most pressing health concerns effectively. Additionally, prevalence data can guide public health efforts in developing targeted prevention strategies and allocating resources appropriately to improve community health outcomes.
A pregnant woman presents with sudden onset of severe lower abdominal pain and syncope. On examination, she appears pale, and her abdomen is distended and tense. Which of the following conditions is the most likely cause of these symptoms?
- A. Ectopic pregnancy
- B. Pelvic inflammatory disease
- C. Placenta previa
- D. Ruptured ovarian cyst
Correct Answer: C
Rationale: Placenta previa is a condition in pregnancy where the placenta implants low in the uterus, partially or completely covering the cervix. This can lead to painless, bright red vaginal bleeding in the third trimester. However, in some cases, placenta previa can also present with sudden onset of severe lower abdominal pain and signs of shock, such as syncope, pallor, and abdominal distention due to concealed bleeding. In severe cases, the bleeding can be significant and life-threatening for both the mother and the baby. It is important to promptly diagnose and manage placenta previa to prevent complications.
A nurse is preparing to assist with a lumbar puncture procedure for a patient. What action should the nurse take to maintain procedural asepsis?
- A. Wearing sterile gloves and a surgical mask during the procedure
- B. Cleansing the puncture site with povidone-iodine solution
- C. Using a sterile drape to cover the patient during the procedure
- D. Avoiding unnecessary movement or talking during the procedure
Correct Answer: A
Rationale: A nurse should wear sterile gloves and a surgical mask during a lumbar puncture procedure to maintain procedural asepsis. Sterile gloves help prevent contamination of the procedure site and reduce the risk of introducing microorganisms to the puncture site. Surgical masks help minimize the risk of respiratory secretions contaminating the sterile field, which is essential for maintaining asepsis during the procedure. Additionally, proper hand hygiene before and after the procedure is crucial in preventing the spread of infection.
What kind of sampling method should she apply?
- A. Network
- B. Stratified
- C. Random
- D. Purposive
Correct Answer: B
Rationale: In a stratified sampling method, the population is divided into subgroups or strata based on certain characteristics that are relevant to the research objective. This allows for representation from each subgroup in the sample, ensuring that different segments of the population are taken into account.