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A patient with Type 2 diabetes mellitus begins gaining weight after several months of therapy with an oral antidiabetic agent. A complete workup indicates edema and other signs and symptoms of heart failure. Which of the following antidiabetic drug or group was the most likely cause?
- A. Acarbose
- B. Biguanides
- C. Glitazones (thiazolidinediones, such as rosiglitazone)
- D. Metformin
Correct Answer: C
Rationale: Glitazones like rosiglitazone can cause fluid retention and weight gain, increasing the risk of heart failure.
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Which of the following glucocorticosteroids are used for cerebral oedema:
- A. Triamcinolon
- B. Prednisolon
- C. Prednison
- D. Dexamethasone
Correct Answer: D
Rationale: Dexamethasone is preferred for cerebral edema due to its potent anti-inflammatory effects and minimal mineralocorticoid activity.
A nurse working in radiology administers iodine to a patient who is having a computed tomography (CT) scan. The nurse working on the oncology unit administers chemotherapy to patients who have cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best describes the actions of all three nurses?
- A. Pharmacoeconomics
- B. Pharmacotherapeutics
- C. Pharmacodynamics
- D. Pharmacokinetics
Correct Answer: B
Rationale: Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help diagnose a disease. The oncology nurse is administering a drug to help treat a disease. Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a drug affects the body and pharmacokinetics is how the body acts on the body.
The first step in the prescribing process according to the World Health Organization is:
- A. Choosing the treatment
- B. Educating the patient about the medication
- C. Diagnosing the patient's problem
- D. Starting the treatment
Correct Answer: C
Rationale: The WHO prescribing process begins with diagnosing the problem to ensure treatment aligns with the condition, followed by choosing therapy and education.
In today's healthcare environment there is often more contact between the patient and the nurse than between the patient and the physician. What does this make the nurse in the best position to do?
- A. Assess the patient's inability to document medication taken
- B. Assess the patient's inability to communicate with caregivers
- C. Assess the therapeutic success of the drug therapy
- D. Assess the patient's reluctance to purchase the prescribed drug
Correct Answer: C
Rationale: Frequent contact positions nurses to evaluate drug therapy success through direct observation and patient feedback.
Which of the following is the indication for glucocorticoid prescribing?
- A. Cataract
- B. Prevention of respiratory distress
- C. Hypofunction of thyroid gland
- D. Hypocalcemia
Correct Answer: B
Rationale: Glucocorticoids are indicated to prevent respiratory distress, such as in preterm infants for lung maturation.