A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the average number of patients that the laboratory should expect to experience side effects if they choose 100 patients at random?
- A. 1
- B. 2
- C. 3
- D. 4
Correct Answer: C
Rationale: The expected value (mean) of a binomial distribution is n * p. Here, n=100 and p=0.03, so U = 100 * 0.03 = 3, as calculated in the document.
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A nurse is reviewing the medical record of a client and notes the various orders for drug therapy. Which of the following would the nurse most likely expect to find? (Select one that does not apply.)
- A. Standing order
- B. STAT order
- C. Single order
- D. Alternate order
Correct Answer: D
Rationale: Common orders given by health care providers for drug therapy include the standing order, the single order, the PRN order, and the STAT order.
A patient with an edema would have an increased volume of distribution (Vd) if?
- A. The patient was taking an anionic drug
- B. The patient was taking a hydrophobic drug
- C. The patient was taking a hydrophilic drug
- D. An edema always causes an increase in Vd
Correct Answer: C
Rationale: Edema increases extracellular fluid, raising Vd for hydrophilic drugs that distribute into this compartment, not hydrophobic drugs (tissue-bound) or universally.
Following are the sign and symptoms of acute morphine poisoning EXCEPT
- A. Respiratory depression with shallow breathing
- B. Hyperthermia
- C. Pin-point pupil
- D. Hypotension
Correct Answer: B
Rationale: Acute morphine poisoning typically causes respiratory depression, miosis (pin-point pupils), and hypotension, but hypothermia, not hyperthermia, is common due to opioid-induced CNS depression.
Which of the following has a strong anti-inflammatory effect:
- A. Prednisolone
- B. Triamcinolone
- C. Dexamethasone
- D. Prednisone
Correct Answer: C
Rationale: Dexamethasone has a strong anti-inflammatory effect due to its high glucocorticoid potency.
The rotavirus vaccine (RotaTeq, Rotarix):
- A. Is a live vaccine that replicates in the small intestine, providing active immunity against rotavirus
- B. Should not be given to infants who are or may be potentially immunocompromised
- C. Is not given to an infant who has a febrile illness (temperature greater than 100.5°F)
- D. All of the above
Correct Answer: D
Rationale: All are true: rotavirus vaccine is live , contraindicated in immunocompromise , and deferred with fever .