A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is angioedema. Which of the following statements is true about this adverse response?
- A. Swelling of the tongue or hoarseness are the most common symptoms.
- B. It appears to be related to the decrease in aldosterone production.
- C. Presence of a dry, hacky cough indicates a high risk for this adverse response.
- D. Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
Correct Answer: A
Rationale: Angioedema presents with tongue swelling or hoarseness and is not linked to cough or aldosterone.
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The nurse administers a prescribed medication that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet. When describing how this tablet is absorbed, which response by the nurse would be most accurate?
- A. The medication dissolves directly from the stomach into the body.'
- B. The drug breaks up into pieces as it moves through the stomach.'
- C. The medication bypasses the GI tract and goes quickly into the bloodstream.'
- D. The drug dissolves into fragments after it reaches your small intestine.'
Correct Answer: D
Rationale: Enteric-coated tablets disintegrate or fragment after reaching the alkaline medium of the small intestine. Tablets and capsules break up into small particles and dissolve into body fluids in the gastrointestinal tract. Liquids and parenteral drugs are quickly absorbed into the body system.
Which of the following drug has the ability to produce hypogliceic effect via closure of ATP-sensitive channels
- A. Glipizide
- B. Metformin
- C. Acarbose
- D. Pramlintide
Correct Answer: A
Rationale: Glipizide, a sulfonylurea, closes ATP-sensitive K+ channels, stimulating insulin release.
In today's health care environment there is often more contact between the patient and the nurse than between the patient and the physician. How does this increased patient contact impact drug therapy?
- A. Choosing the best medication to treat the patient's condition
- B. Assessing the patient's preferred communication strategies
- C. Assessing the therapeutic success of the drug therapy
- D. Reducing dosage quickly when adverse effects arise
Correct Answer: C
Rationale: More contact allows nurses to assess therapy success through observation and patient feedback.
Patient education when prescribing colchicine includes:
- A. Colchicine may be constipating
- B. Colchicine always causes some degree of diarrhea
- C. Mild muscle weakness is normal
- D. Moderate amounts of alcohol are safe with colchicine
Correct Answer: B
Rationale: Colchicine commonly causes diarrhea, not constipation ; weakness or alcohol aren't typical advice.
Which medication ordered for a patient with a substance abuse history has the greatest risk for abuse?
- A. Lomotil
- B. Diazepam
- C. Phenobarbital
- D. Lortab
Correct Answer: D
Rationale: Lortab is a Schedule III drug with a higher potential for abuse than Lomotil (Schedule V), Diazepam (Schedule IV), and Phenobarbital (Schedule IV).
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