Nokea
Colestipol comes in a powdered form. The patient is taught to:
- A. Take the powder dry and follow it with at least 8 ounces of water
- B. Take it with a meal to enhance its action on fatty food
- C. Mix the powder with 4 to 6 ounces of milk or fruit juice
- D. Take after the evening meal to coincide with cholesterol synthesis
Correct Answer: C
Rationale: Mixing colestipol with liquid improves palatability and administration.
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Frusemide is:
- A. A loop diuretic
- B. Osmotic diuretic
- C. Aldosterone antagonist
- D. A carbonic anhydrase inhibitor
Correct Answer: A
Rationale: Furosemide (Frusemide) is a loop diuretic that inhibits sodium and chloride reabsorption in the loop of Henle, leading to increased urine output.
Which of the following drug has the ability to produce hypogliceic effect via closure of ATP-sensitive channels
- A. Glipizide
- B. Metformin
- C. Acarbose
- D. Pramlintide
Correct Answer: A
Rationale: Glipizide, a sulfonylurea, closes ATP-sensitive K+ channels, stimulating insulin release.
Osteoporosis is a major adverse effect caused by the glucocorticoids. It is due to their ability to:
- A. Increase the excretion of calcium
- B. Inhibit absorption of calcium
- C. Stimulate the hypothalamic-pituitary-adrenal axis
- D. Decrease production of prostaglandins
Correct Answer: B
Rationale: Glucocorticoids inhibit calcium absorption in the gut, contributing to osteoporosis.
Antiemitic used to prevent aspiration in emergency surgery
- A. Ondansetrone
- B. Promethazine
- C. Metoclopromide
- D. Ranitidine
Correct Answer: B
Rationale: Promethazine (antihistamine) prevents aspiration with sedative effects.
The following drugs may precipitate angina pectoris EXCEPT:
- A. Amphetamine
- B. Hydralazine
- C. Isoproterenol
- D. Epinephrine
Correct Answer: D
Rationale: Propranolol, a beta-blocker, relieves angina, unlike the others which increase cardiac demand.