Nokea
A prescription needs to be written for:
- A. Legend drugs
- B. Most controlled drugs
- C. Medical devices
- D. All of the above
Correct Answer: D
Rationale: Prescriptions are required for legend drugs (prescription-only), most controlled drugs, and certain medical devices , per regulatory standards.
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Common side effect of isoniazide:
- A. Hepatitis
- B. Ototoxicity
- C. Visual toxicity
- D. Hepatitis
Correct Answer: A
Rationale: Isoniazid (likely misspelled as Isoniazide) commonly causes hepatitis as a side effect due to its hepatotoxic potential, requiring liver function monitoring. Note: Option D repeats 'Hepatitis,' but A is intended.
The choice of diuretic to use in treating hypertension is based on:
- A. Presence of diabetes with loop diuretics being used for these patients
- B. Level of kidney function with a thiazide diuretic being used for an estimated glomerular filtration rate higher than the mid-40 mL/min range
- C. Ethnicity with aldosterone antagonists best for African Americans and older adults
- D. Presence of hyperlipidemia with higher doses needed for patients with LDL above 130 mg/dL
Correct Answer: B
Rationale: Thiazides are effective with GFR >40-50 mL/min; loops are used for lower GFR.
Which of the following drugs interacts with nitroglycerine by inhibiting the metabolism of cGMP?
- A. Amyl nitrite
- B. Sildenafil
- C. Isosorbide mononitrate
- D. Nifedipine
Correct Answer: B
Rationale: Sildenafil, a PDE5 inhibitor, increases cGMP, enhancing nitroglycerin's hypotensive effect.
A nurse is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. The nurse should set the IV pump to deliver how many mL/hr? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 200
- B. 180
- C. 250
- D. 500
Correct Answer: A
Rationale: Calculation: (100 mL / 30 min) 60 min/hr = 200 mL/hr, matching the provided answer.
Larry is taking allopurinol to prevent gout. Monitoring of a patient who is taking allopurinol includes:
- A. Complete blood count
- B. Blood glucose
- C. C-reactive protein
- D. BUN, creatinine, and creatinine clearance
Correct Answer: D
Rationale: Allopurinol requires renal function monitoring (BUN, creatinine) due to toxicity risk; CBC is less routine.