Nokea
A specific sequence of three consecutive nucleotides that is part of the genetic code and that specifies a particular amino acid in a protein or starts or stops protein synthesis is called:
- A. Codon
- B. Primer
- C. Nucleosome
- D. Polypeptide
Correct Answer: A
Rationale: Step 1: Definition - A codon is a sequence of three nucleotides that code for a specific amino acid or signal the start/stop of protein synthesis.
Step 2: Function - Codons are essential for translating genetic information into proteins.
Step 3: Specificity - Codons are specific in their role of encoding amino acids.
Step 4: Examples - Examples like AUG for methionine and UAA, UAG, UGA for stop codons illustrate codon functionality.
Step 5: Summary - The correct answer is A (Codon) because it accurately describes the function and specificity of a three-nucleotide sequence in genetic coding. Choices B, C, and D are incorrect as they do not align with the definition and function of a codon.
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In which of the following GIT infections, the bacteria adhere to the intestine wall and damage the microvilli:
- A. Enteropathogenic E. Coli (EPEC)
- B. Enterohemorrhagic E. Coli (EHEC)
- C. Enterotoxigenic E Coli (ETEC)
- D. Enteroinvasive E Coli (EIEC)
Correct Answer: A
Rationale: The correct answer is A: Enteropathogenic E. Coli (EPEC). EPEC bacteria adhere to the intestine wall using a protein called intimin, leading to microvilli damage. This attachment disrupts the normal absorption function of the intestine.
Summary of why other choices are incorrect:
B: Enterohemorrhagic E. Coli (EHEC) primarily causes bloody diarrhea and does not specifically target microvilli.
C: Enterotoxigenic E. Coli (ETEC) produces toxins that lead to watery diarrhea but does not directly target microvilli.
D: Enteroinvasive E. Coli (EIEC) invades and replicates within intestinal cells, causing inflammatory diarrhea, but does not specifically damage microvilli.
Which form of human plague is present with high fever and large lymphadenopathies (buboes). The case fatality in untreated cases may reach 60%.
- A. Bubonic plague
- B. Pneumonic plague
- C. Gastrointestinal plague
- D. Septicemic plague
Correct Answer: A
Rationale: The correct answer is A: Bubonic plague. Bubonic plague is characterized by high fever and large swollen lymph nodes (buboes). The case fatality rate in untreated cases can reach 60%. This form of plague is typically transmitted through the bite of an infected flea.
B: Pneumonic plague presents with respiratory symptoms and is transmitted through respiratory droplets.
C: Gastrointestinal plague is not a recognized form of plague.
D: Septicemic plague is a severe form of plague where the bacteria multiply in the bloodstream. It may not always present with buboes.
Which bacteria produce exotoxins that affect the nervous system?
- A. Clostridium botulinum and Clostridium tetani
- B. Escherichia coli and Salmonella
- C. Bacillus anthracis and Listeria monocytogenes
- D. Pseudomonas aeruginosa and Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms.
Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.
Which bacteria are commonly associated with food poisoning?
- A. Clostridium botulinum and Staphylococcus aureus
- B. Bacillus anthracis and Mycobacterium tuberculosis
- C. Treponema pallidum and Neisseria gonorrhoeae
- D. Escherichia coli and Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Staphylococcus aureus. Clostridium botulinum produces a potent neurotoxin causing botulism, commonly associated with improperly canned foods. Staphylococcus aureus produces toxins causing symptoms of food poisoning. Bacillus anthracis and Mycobacterium tuberculosis are not typically associated with food poisoning. Treponema pallidum and Neisseria gonorrhoeae are bacteria causing sexually transmitted infections. Escherichia coli and Klebsiella pneumoniae are not directly linked to food poisoning.
Which of the following statements is FALSE regarding B cells?
- A. B cells that recognize high concentrations of antigen (self) in the absence of other signals undergo apoptosis in the bone marrow
- B. Bone marrow stem cells migrate to the thymus and develop into B cells
- C. B cells synthesize antibodies and put them on their cell surface
- D. B cells can undergo class switching and produce a different antibody type
Correct Answer: B
Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.