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Acyclovir is the drug of choice for which condition?

  • A. HIV
  • B. HSV 1 and 2 and VZV
  • C. CMV
  • D. influenza A viruses
Correct Answer: B

Rationale: Acyclovir is a nucleoside analog antiviral drug that is specifically effective against herpes simplex virus (HSV) types 1 and 2, as well as varicella-zoster virus (VZV). The drug works by inhibiting viral DNA synthesis. HSV and VZV are both members of the herpes virus family, and acyclovir is most commonly prescribed for infections caused by these viruses. Therefore, the correct answer is B.

Choice A (HIV) is incorrect because acyclovir is not effective against HIV. Choice C (CMV) is incorrect because acyclovir is less effective against cytomegalovirus (CMV) compared to HSV and VZV. Choice D (influenza A viruses) is incorrect because acyclovir is not indicated for the treatment of influenza viruses.