Adenoviruses have helical capsids:
- A. TRUE
- B. FALSE
- C. Both answers can be correct depending on the given situation
- D. None of the above
Correct Answer: B
Rationale: Step 1: Adenoviruses are known to have icosahedral capsids, not helical.
Step 2: Helical capsids are typically found in viruses like tobacco mosaic virus.
Step 3: Therefore, the statement that adenoviruses have helical capsids is FALSE.
Summary: A is incorrect as adenoviruses do not have helical capsids. C is incorrect as there is no situation where adenoviruses have helical capsids. D is incorrect as there is a clear correct answer, which is B.
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By precipitation of tuberculin, a purified protein derivative (PPD) is obtained. It is used in:
- A. Mantoux test
- B. Schick test
- C. Dick test
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A: Mantoux test. The Mantoux test is used to screen for tuberculosis by injecting PPD intradermally. The presence of a delayed hypersensitivity reaction indicates prior exposure to Mycobacterium tuberculosis. The Schick test (B) is used to test for immunity to diphtheria, while the Dick test (C) is used to test for immunity to scarlet fever. Therefore, the correct use of PPD is in the Mantoux test for tuberculosis screening.
Which bacterial structure allows for attachment to host cells?
- A. Flagella
- B. Fimbriae
- C. Capsule
- D. Endospore
Correct Answer: B
Rationale: The correct answer is B: Fimbriae. Fimbriae are hair-like appendages found on the surface of bacteria that enable attachment to host cells. This attachment is crucial for establishing infection. Flagella (A) are used for movement, not attachment. Capsules (C) provide protection and help evade the host immune system, but do not directly facilitate attachment. Endospores (D) are dormant structures for survival, not for attachment to host cells. Fimbriae specifically aid in adherence to host cells, making them the correct choice in this context.
Which of the following bacteria is known to cause strep throat?
- A. Streptococcus pyogenes
- B. Staphylococcus aureus
- C. Neisseria gonorrhoeae
- D. Clostridium tetani
Correct Answer: A
Rationale: Step 1: Streptococcus pyogenes is commonly known as Group A Streptococcus, which is the primary bacteria responsible for causing strep throat.
Step 2: Staphylococcus aureus is not typically associated with strep throat but can cause skin infections and other illnesses.
Step 3: Neisseria gonorrhoeae is the bacteria responsible for gonorrhea, a sexually transmitted infection, not strep throat.
Step 4: Clostridium tetani causes tetanus, a bacterial infection that affects the nervous system and is not related to strep throat.
A 34 year old male patient consulted a doctor about face carbuncle. Objectively: a loose, painless edema of hypodermic tissue; black crust in the center of carbuncle, vesicular rash around it. Microbiological examination revealed static streptobacilli capable of capsule building. What microorganisms are the causative agents of this disease?
- A. Bacillus antracis
- B. Staptylococcus aureus
- C. Bacillus subtilis
- D. Bacillus anthracoides
Correct Answer: B
Rationale: The correct answer is B: Staphylococcus aureus. This bacterium is a common causative agent of skin infections like carbuncles. Staphylococcus aureus is known for its ability to produce pus-filled abscesses, which aligns with the symptoms described in the question. The presence of a vesicular rash around the carbuncle further supports this diagnosis, as Staphylococcus aureus can cause skin lesions. The other choices are not correct because:
A: Bacillus anthracis causes anthrax, which presents with different symptoms such as fever, malaise, and respiratory symptoms.
C: Bacillus subtilis is a harmless soil bacterium commonly used in research and not known to cause skin infections.
D: Bacillus anthracoides is not a known pathogen and is not associated with human infections.
Microscopy of a wound abscess revealed Gram-negative rods producing blue-green pigment with a distinctive odor of jasmine. What is the likely causative agent?
- A. Pseudomonas aeruginosa
- B. Proteus vulgaris
- C. Escherichia coli
- D. Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known for producing a blue-green pigment called pyocyanin, which gives the characteristic color seen in the wound abscess. The distinctive odor of jasmine is also a key feature of Pseudomonas aeruginosa. Proteus vulgaris (B) and Klebsiella pneumoniae (D) do not produce blue-green pigment or have a jasmine-like odor. Escherichia coli (C) typically does not produce blue-green pigment or have a jasmine-like odor.
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