Nokea
Adherence to beta blocker therapy may be affected by their:
- A. Short half-lives requiring twice daily dosing
- B. Tendency to elevate lipid levels
- C. Effects on the male genitalia, which may produce impotence
- D. None of the above
Correct Answer: C
Rationale: Impotence is a known side effect that can reduce adherence to beta blockers.
You may also like to solve these questions
Identify poor metabolizers of tamoxifen
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: C
Rationale: This question lacks options, but the answer key (ANS: 3) indicates the third choice. Poor metabolizers of tamoxifen can be identified through CYP2D6 genotyping, as this enzyme converts tamoxifen to its active metabolite.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh 64 kg or less.
- A. 5
- B. 11
- C. 15
- D. 20
Correct Answer: B
Rationale: P(X ≤ 64) equals P(X < 64) in a continuous distribution since P(X=64) = 0. From the previous calculation, P(Z < -2) ≈ 0.0228, so 0.0228 * 500 ≈ 11, consistent with the document.
Under new U.S. Food and Drug Administration labeling, Pregnancy Categories will be:
- A. Strengthened with a new coding such as C+ or C- to discern when a drug is more or less toxic to the fetus
- B. Changed to incorporate a pregnancy risk summary and clinical considerations on the drug label
- C. Eliminated, and replaced with a link to the National Library of Medicine TOXNET Web site for in-depth information regarding pregnancy concerns
- D. Clarified to include information such as safe dosages in each trimester of pregnancy
Correct Answer: B
Rationale: FDA replaced categories with risk summaries and clinical considerations for clearer, narrative-based guidance, effective 2015.
Which of the following statements is correct?
- A. Most drags are absorbed in ionized form
- B. Basic drags are generally bound to plasma albumin
- C. Microsomal enzymes are located in the mitochondria of hepatic cells
- D. Blood brain barrier is deficient at the chemo receptor trigger-zone
Correct Answer: D
Rationale: The chemoreceptor trigger zone has a deficient blood-brain barrier, allowing drug access; others are incorrect.
The clinic nurse is performing an admission assessment on a client. The nurse notes that the client is taking azelaic acid (Azelex). Because of the medication prescription, the nurse would suspect that the client is being treated for:
- A. Acne
- B. Eczema
- C. Hair loss
- D. Herpes simplex
Correct Answer: A
Rationale: Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to work by suppressing the growth of Propionibacterium acnes and decreasing the proliferation of keratinocytes. Options 2, 3, and 4 are incorrect.