After a 3- month trail of dietary therapy, a client with type2 diabetes mellitus still has blood glucose levels above 180 mg/dl. The physician adds glyburide (DiaBeta), 2.5 mg P.O. daily, to the treatment regimen. The nurse should instruct the client to take glyburide:
Correct Answer: D
Rationale: Glyburide (DiaBeta) is a sulfonylurea medication used to treat type 2 diabetes mellitus by stimulating the pancreas to release more insulin. Taking glyburide at bedtime is recommended because it helps to ensure that the medication's peak action aligns with the natural rise in blood glucose levels in the early morning hours, which can help control fasting blood glucose levels. Additionally, taking glyburide in the evening reduces the risk of hypoglycemia during the day when the client may be more active and less likely to monitor blood glucose levels closely.