After administering methoxy polyethylene epoetin beta, the nurse would be alert for the development of which of the following as a possible adverse reaction? Select all that apply.
- A. Bone pain
- B. Fluid retention
- C. Hypertension
- D. Fatigue
- E. Arthralgia
Correct Answer: C,D,E
Rationale: Hypertension, headache, nausea, vomiting, diarrhea, rashes, fatigue, arthralgia, and injection site skin reactions are adverse reactions the nurse should discuss with a client prior to the administration of methoxy polyethylene epoetin beta (Mircera).
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A nursing instructor is conducting a class on the different types of blood cells. Which of the following would the instructor include as the correct function? Select all that apply.
- A. Erythrocytes supply our cells with oxygen from the lungs to the tissues.
- B. Erythrocytes control bleeding from microscopic to major tears in our tissues.
- C. Leukocytes supply our cells with oxygen from the lungs to the tissues.
- D. Leukocytes protect the body from dangerous organisms.
- E. Megakaryocytes control bleeding from microscopic to major tears in our tissues.
Correct Answer: A,D,E
Rationale: Erythrocytes supply our cells with oxygen from the lungs to the tissues; leukocytes protect the body from dangerous organisms; and megakaryocytes control bleeding from microscopic to major tears in our tissues.
Based on the nurse's understanding of epoetin alfa, the nurse would expect to administer the drug cautiously to a client with a history of which of the following? Select all that apply.
- A. Diabetes
- B. Renal failure
- C. History of seizures
- D. Congestive heart failure
- E. Hypotension
Correct Answer: C,D
Rationale: Epoetin alfa (Procrit) is used cautiously in clients with hypertension, heart disease, congestive heart failure, or a history of seizures.
A client has a hypersensitivity reaction to pegfilgrastim (Neufasta). The nurse would expect to administer which of the following to treat the hypersensitivity reaction and maintain the use of colony-stimulating factors? Select all that apply.
- A. Prednisone
- B. Diphenhydramine
- C. Albuterol
- D. Naproxen
- E. Hydrocodone
Correct Answer: A,B,C
Rationale: Colony-stimulating factors, like pegfilgrastim (Neulasta), can cause hypersensitivity reactions and should be treated with antihistamines (diphenhydramine), steroids (prednisone), and bronchodilators (albuterol) to maintain their use.
A client is to receive darbepoetin alfa (Aranesp). When administering the drug, the nurse integrates knowledge of which of the following? Select all that apply.
- A. The drug is a glycoprotein.
- B. It is used to stimulate the production of erythrocytes.
- C. It helps stimulate differentiation of leukocytes.
- D. The drug promotes the maturation of megakaryocytes.
- E. It is used to stimulate thrombopoiesis
Correct Answer: A,B
Rationale: The following is true of the drug darbepoetin alfa (Aranesp): it is a glycoprotein, erythropoiesis-stimulating agent used to stimulate and regulate the production of erythrocytes (erythropoiesis).
A nurse should encourage a client with megaloblastic anemia to eat which of the following foods, as they are rich in folate? Select all that apply.
- A. Collard greens
- B. Grapes
- C. Wheat bread
- D. Salmon
- E. Chicken
Correct Answer: A,C,D,E
Rationale: A deficiency of folic acid (folate) results in megaloblastic anemia, and the nurse should encourage a client to eat foods rich in folic acid including leafy green vegetables (collard greens), fish (salmon), meat, poultry (chicken), and whole grains (wheat bread).
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