After teaching a group of nursing students about upper gastrointestinal system drugs, the instructor determines that the teaching was successful when the students identify which of the following as a gastrointestinal stimulant?
- A. Ranitidine (Zantac)
- B. Misoprostol (Cytotec)
- C. Omeprazole (Prilosec)
- D. Metoclopramide (Reglan)
Correct Answer: D
Rationale: Metoclopramide (Reglan) is classified as a gastrointestinal stimulant. Ranitidine is a histamine-2 receptor antagonist. Omeprazole is a proton pump inhibitor. Misoprostol is a miscellaneous acid reducer.
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A client with a nasogastric tube is prescribed therapy to prevent ulcer development. Which of the following would be the best option for the drug?
- A. Tablet that can be crushed
- B. Liquid formulation
- C. Intravenous administration
- D. Intramuscular injection
Correct Answer: B
Rationale: The nurse should request the liquid form when administration is in a tube to decrease the chance of a clogged NG tube. Although it is appropriate to crush the tablet and mix it with apple juice, there is still a risk for clogging. Intravenous or intramuscular administration would be inappropriate. The IV route is typically preferred if the patient has an existing IV line, because these drugs are irritating, and IM injections need to be given deep into the muscular tissue to minimize harm.
A nurse is caring for an elderly client who has received cimetidine. Which of the following interventions should the nurse perform?
- A. Monitor the client for complaints of pain or sour taste.
- B. Monitor the client for concentrated urine and restlessness.
- C. Closely monitor the client for confusion and dizziness.
- D. Report symptoms of tardive dyskinesia to the primary health care provider.
Correct Answer: C
Rationale: The nurse should closely monitor the elderly client who has been administered cimetidine for confusion and dizziness. When the client is receiving an antiemetic, the nurse monitors the client frequently for continued complaints of pain, sour taste, spitting blood, or coffee-ground-colored emesis. When antacids are given to the client, the nurse should observe the client for concentrated urine and restlessness. When the client is administered prolonged doses of metoclopramide, the nurse reports any sign of tardive dyskinesia or extrapyramidal symptoms to the primary health care provider.
A client is prescribed ranitidine. A review of the client's medication history reveals that she also takes warfarin for treatment of deep vein thrombosis. The nurse would monitor the client for which of the following?
- A. Decreased white blood cell count
- B. Increased risk of respiratory depression
- C. Increased risk for bleeding
- D. Decreased seizure threshold
Correct Answer: C
Rationale: Histamine-2 receptor antagonists when given with warfarin place the client at an increased risk for bleeding. A decreased white blood cell count occurs when histamine-2 receptor antagonists are given with carmustine. An increased risk of respiratory depression occurs when histamine-2 receptor antagonists are given with opioid analgesics. This class of drugs does not interact with any antiseizure medications.
A nurse is caring for a client who has been prescribed aluminum carbonate gel (Basaljel) for the relief of an acute peptic ulcer. Which of the following interventions should the nurse perform to promote an optimal response to therapy?
- A. Administer the drug hourly for the first 2 weeks.
- B. Administer the drug early in the morning before breakfast.
- C. Administer the drug with 40 mL of apple juice.
- D. Administer the first dose by IV route and then orally.
Correct Answer: A
Rationale: The nurse should administer the drug hourly for the first 2 weeks when treating an acute peptic ulcer. The nurse instructs the client to administer the drug 1 to 2 hours after meals and at bedtime after the first 2 weeks. The nurse need not suggest to the client to administer the drug early to the morning before breakfast nor to administer it with apple juice. The drug is not given intravenously.
Which of the following antacids may have a laxative effect and should be used cautiously in clients who have chronic diarrhea?
- A. Calcium carbonate (Mylanta)
- B. Magnesium hydroxide (Milk of Magnesia)
- C. Magnesium oxide (Mag-Ox)
- D. Aluminum hydroxide (ALternaGEL)
- E. Sodium bicarbonate (Bell/ans)
Correct Answer: B,C,E
Rationale: The magnesium- and sodium-containing antacids may have a laxative effect and may produce diarrhea. Aluminum- and calcium-containing antacids tend to produce constipation.
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