Nokea
After teaching a patient with HIV infection about using antiretroviral drugs, the nurse recognizes that further teaching is needed when the patient says
- A. I should never skip doses of my medication, even if I develop side effects.
- B. If my viral load becomes undetectable, I will no longer be able to transmit HIV to others.
- C. I should not use any over-the-counter drugs without checking with my health care provider.
- D. If I develop a constant headache that is not relieved with aspirin or acetaminophen, I should report it within 24 hours.
Correct Answer: B
Rationale: Even with an undetectable viral load, HIV can still potentially be transmitted, especially during certain activities like unprotected sex.
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Indicate the incorrect statement. Chronic granulomatous disease is
- A. Caused by defective recruitment of neutrophils to sites of infection
- B. Associated with defective respiratory burst of neutrophils
- C. Caused by mutations of the NADPH oxidase genes
- D. Associated with recurrent bacterial infections
Correct Answer: A
Rationale: The correct answer is A. Chronic granulomatous disease (CGD) is caused by mutations of the NADPH oxidase genes, leading to defective respiratory burst in neutrophils. Neutrophils are recruited to sites of infection normally in CGD. Therefore, choice A is incorrect. Choices B, C, and D are incorrect because CGD is indeed associated with defective respiratory burst of neutrophils due to mutations in NADPH oxidase genes, leading to recurrent bacterial infections.
Determine the following diseases that are not thought to be an autoimmune disease.
- A. Rheumatoid arthritis
- B. Multiple sclerosis
- C. Cancer of the bone marrow
- D. Insulin-dependent diabetes
Correct Answer: C
Rationale: The correct answer is C, Cancer of the bone marrow. Autoimmune diseases occur when the immune system mistakenly attacks healthy cells. Rheumatoid arthritis, multiple sclerosis, and insulin-dependent diabetes are autoimmune diseases where the immune system targets specific tissues or organs. Cancer of the bone marrow, on the other hand, is a result of uncontrolled cell growth and division, not a malfunction of the immune system attacking the body's own tissues. Therefore, it is not considered an autoimmune disease.
Ribosomes associated with cells or organelles have a certain size, which is expressed in Svedberg units. Which associations are incorrect?
- A. cyanobacteria - 80s
- B. chloroplasts - 60s
- C. photosynthetic bacteria - 80s
- D. green algal cytoplasm - 80s
Correct Answer: A
Rationale: The correct answer is A because cyanobacteria have ribosomes measured in 70s, not 80s. Ribosomes in prokaryotes are either 70s (composed of 50s and 30s subunits) or 80s in eukaryotes (60s and 40s subunits). Choices B, C, and D are incorrect because chloroplasts, photosynthetic bacteria, and green algal cytoplasm all have ribosomes measured in 70s or 80s, consistent with their cell types.
A patient with chronic kidney disease has hyperphosphatemia. What is a commonly associated electrolyte imbalance?
- A. Hypokalemia
- B. Hyponatremia
- C. Hypocalcemia
- D. Hypomagnesemia
Correct Answer: C
Rationale: Hyperphosphatemia binds calcium, lowering its availability and causing hypocalcemia in patients with chronic kidney disease.
Which represents a correct grouping with respect to the target of an immune response, immune response strength, and resulting health status?
- A. Self-antigen, weak response, autoimmune disease
- B. Pathogen, strong response, recurrent infection
- C. Tumour antigen, weak response, cancer
- D. Transplanted organ, strong response, graft acceptance
Correct Answer: C
Rationale: Rationale:
1. Tumor antigens are non-self antigens that trigger a weak immune response due to immune tolerance.
2. Weak immune response against tumor antigens may lead to uncontrolled cell growth, resulting in cancer.
3. Strong immune responses are typically mounted against pathogens to clear infections.
4. Self-antigens should not trigger immune responses to prevent autoimmune diseases.
5. Transplanted organs can elicit strong immune responses leading to rejection, not acceptance.
Summary:
A - Incorrect: Self-antigens should not elicit immune responses to prevent autoimmune diseases.
B - Incorrect: Pathogens typically trigger strong immune responses to clear infections, not recurrent ones.
D - Incorrect: Transplanted organs often lead to strong immune responses and rejection, not acceptance.