Nokea
Which scientist is credited with identifying Toll-like receptors (TLRs) in innate immunity?
- A. Paul Ehrlich
- B. Jules Hoffman
- C. Edward Jenner
- D. Louis Pasteur
Correct Answer: B
Rationale: The correct answer is B: Jules Hoffman. He is credited with identifying Toll-like receptors (TLRs) in innate immunity. Hoffman's research provided crucial insights into how the immune system recognizes pathogens and triggers immune responses. Paul Ehrlich is known for his work on antibodies, Edward Jenner for developing the smallpox vaccine, and Louis Pasteur for his contributions to germ theory and vaccination. However, none of them are specifically associated with the discovery of Toll-like receptors in innate immunity.
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The recirculation of naïve lymphocytes follows which sequential order?
- A. Blood, HEV, LN, efferent lymphatics, thoracic duct, blood
- B. Blood, afferent lymphatics, LN, thoracic duct, blood
- C. Inflammatory sites, afferent lymphatics, LN, efferent lymphatics, thoracic duct, blood
- D. Both A and C are correct
Correct Answer: A
Rationale: The correct answer is A because naïve lymphocytes circulate through blood, enter lymph nodes (LN) via high endothelial venules (HEV), encounter antigens in LN, exit via efferent lymphatics, drain into the thoracic duct, and return to blood circulation. Choice B is incorrect because it skips the step of entering LN through HEV. Choice C is incorrect because it starts with inflammatory sites instead of blood, and it also lacks the step of entering LN through HEV. Choice D is incorrect as only option A correctly follows the sequential order of recirculation of naïve lymphocytes.
Priority Decision: While caring for a patient who is at the nadir of chemotherapy, the nurse establishes the highest priority for nursing actions related to
- A. diarrhea
- B. grieving
- C. risk for infection
- D. inadequate nutritional intake
Correct Answer: C
Rationale: At the nadir, the patient's white blood cell count is lowest, increasing the risk for infection, making it the highest priority.
As the hospital employee health nurse,you are completing a health history for a newly hired nursing assistant. Which information given by the new employee most indicates the need for further nursing action prior to orienting the nursing assistant to patient care?
- A. The new employee takes enalapril (Vasotec) for hypertension.
- B. The new employee is allergic to bananas,avocados and papayas.
- C. The new employee received a tetanus vaccination 3 years ago.
- D. The new employee’s TB skin test has a 5-mm induration at 48 hours.
Correct Answer: D
Rationale: A 5-mm induration on a TB skin test is considered positive in healthcare workers indicating possible exposure to tuberculosis. This requires further evaluation and possibly treatment before the nursing assistant can safely care for patients. The other information while important does not pose an immediate risk to patient care.
Cancer cells go through stages of development. What accurately describes the stage of promotion (select all that apply)?
- A. Obesity is an example of a promoting factor
- B. The stage is characterized by increased growth rate and metastasis
- C. Withdrawal of promoting factors will reduce the risk of cancer development
- D. Tobacco smoke is a complete carcinogen that is capable of both initiation and promotion
Correct Answer: C
Rationale: Promotion involves enhancing the growth of initiated cells. Obesity and tobacco smoke are examples of promoting factors, and withdrawal of such factors can reduce cancer risk.
What type of antibodies predominate in the secondary immune response?
- A. IgM
- B. IgE
- C. IgG
- D. IgD
Correct Answer: C
Rationale: The correct answer is C: IgG. In the secondary immune response, IgG antibodies predominate due to memory B cells rapidly producing them upon re-exposure to the same antigen. IgG provides long-lasting immunity and is more efficient in neutralizing pathogens. IgM (A) is the primary antibody in the initial immune response. IgE (B) is involved in allergic reactions. IgD (D) functions as a receptor on B cells.