Aminoglycosides are poorly absorbed from the gut and must therefore be delivered via parenteral routes.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Aminoglycosides have poor oral bioavailability due to their polar nature, requiring parenteral administration (e.g., IV or IM) for systemic effects.
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In which type of cell are ligand-gated ion channels most commonly found?
- A. Cells that are terminally differentiated
- B. Cells that produce large proteins
- C. Cells that need to respond quickly to external stimuli
- D. Cells that respond to mechanic forces
Correct Answer: C
Rationale: Ligand-gated ion channels enable rapid responses to stimuli, common in excitable cells like neurons and muscle cells.
What dermatological issue is linked to Amiodarone use?
- A. Increased risk of basal cell carcinoma
- B. Flare up of any prior psoriasis problems
- C. Development of plantarwarts
- D. Progressive change of skin tone toward a blue spectrum
Correct Answer: D
Rationale: Amiodarone causes blue-gray skin discoloration due to drug deposition.
Who defines the standards of care for the practice of nursing? (Select one that does not apply.)
- A. State boards of nursing
- B. Hospital policy and procedures
- C. Federal laws regulating health care facilities
- D. The Joint Commission
Correct Answer: B
Rationale: Standards of care are defined by state boards of nursing, federal laws regulating health care facilities, The Joint Commission, and professional nursing associations such as the American Nurses Association. Individual hospital policies and procedures incorporate federal and state guidelines into their respective policies and procedures and are often more stringent than state and federal regulations.
A nurse is reviewing the health care record of a client who reports urinary incontinence and asks about a prescription for Oxybutynin. The nurse should recognize that Oxybutynin is contraindicated in the presence of which of the following conditions?
- A. Bursitis
- B. Brussels
- C. Depression
- D. Glaucoma
Correct Answer: D
Rationale: Oxybutynin is contraindicated in glaucoma due to its anticholinergic effects increasing intraocular pressure.
Which of the following drug increase the sensitivity of fatty tissue and muscles towards insulin:
- A. Dapagliphlozin
- B. Miglitol
- C. Nateglinide
- D. Rosiglitasone
Correct Answer: D
Rationale: Rosiglitazone, a thiazolidinedione, enhances insulin sensitivity in fat and muscle via PPAR-gamma activation.