Nokea
Aminoglycosides lack activity against streptococci.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Aminoglycosides are effective against some streptococci (e.g., when combined with cell wall-active agents), though they are primarily used for gram-negative bacteria.
You may also like to solve these questions
Which of the following drug can cause hypoglycemia:
- A. Acarbose
- B. Glipizide
- C. Metformin
- D. Pramlintide
Correct Answer: B
Rationale: Glipizide, a sulfonylurea, can cause hypoglycemia by excessively stimulating insulin release from pancreatic beta cells.
Patient teaching related to amlodipine includes:
- A. Increase calcium intake to prevent osteoporosis from a calcium blockade.
- B. Do not crush the tablet; it must be given in liquid form if the patient has trouble swallowing it.
- C. Avoid grapefruit juice as it affects the metabolism of this drug.
- D. Rise slowly from a supine position to reduce orthostatic hypotension.
Correct Answer: C
Rationale: Grapefruit juice inhibits CYP3A4, increasing amlodipine levels.
All are true except
- A. Acidic drugs bind to albumin & basic to acid glucoprotein
- B. All drugs have the same binding sites and mev compete for them
- C. Increased dosage will cause decrease in free drug in plasma throughout the therapeutic range
Correct Answer: D
Rationale: Acidic drugs bind albumin, basic drugs bind alpha-1-acid glycoprotein; binding sites differ, and increased dosage increases free drug levels.
Nicotine gum products are:
- A. Chewed to release the nicotine and then swallowed for a systemic effect
- B. Parked' in the buccal area of the mouth to produce a constant amount of nicotine release
- C. Bound to exchange resins so the nicotine is only released during chewing
- D. Approximately the same in nicotine content as smoking two cigarettes
Correct Answer: B
Rationale: Nicotine gum is parked buccally for steady release.
When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
- A. Working with animals who are given experimental drugs
- B. Choosing appropriate patients to be involved in the drug study
- C. Monitoring and observing patients closely for adverse effects
- D. Conducting research to determine effectiveness of the drug
Correct Answer: C
Rationale: Phase III studies involve use of a drug in a vast clinical population in which patients are asked to record any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect and analyze the information to be shared with the Food and Drug Administration (FDA) but would not conduct research independently because nurses do not prescribe medications. Use of animals in drug testing is done in the preclinical trials. Select patients who are involved in phase II studies to participate in studies where the participants have the disease the drug is intended to treat. These patients are monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.