LPN Nursing Questions Related to Pharmacology Related

Review LPN Nursing Questions Related to Pharmacology related questions and content

An example of a first-dose reaction that may occur includes:

  • A. Orthostatic hypotension that does not occur with repeated doses
  • B. Purple glove syndrome with phenytoin use
  • C. Hemolytic anemia from ceftriaxone use
  • D. Contact dermatitis from neomycin use
Correct Answer: A

Rationale: Choice A is correct because orthostatic hypotension can occur with a first dose of drugs like antihypertensives, subsiding as the body adjusts, a classic first-dose reaction. Choice B is incorrect as purple glove syndrome is a rare phenytoin effect, not first-dose specific. Choice C is wrong because hemolytic anemia is a type II reaction, not first-dose. Choice D is incorrect since contact dermatitis is a delayed, not first-dose, reaction.