Nokea
An HIV-positive patient who has been started on antiretroviral therapy (ART) is seen in the clinic for follow-up. Which test will be most helpful in determining the response to therapy?
- A. Lymphocyte count
- B. ELISA testing
- C. Western blot analysis
- D. Viral load testing
Correct Answer: D
Rationale: Viral load testing measures the amount of HIV RNA in the blood and is the most direct way to assess the effectiveness of antiretroviral therapy. A decrease in viral load indicates that the therapy is working. The other tests provide useful information but are not as directly related to the effectiveness of ART.
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What type of cell is responsible for carrying oxygen and carbon dioxide in the body?
- A. Red blood cell
- B. White blood cell
- C. Platelet
- D. Hematocrit
Correct Answer: A
Rationale: The correct answer is A: Red blood cell. Red blood cells, also known as erythrocytes, contain hemoglobin that binds to oxygen and carbon dioxide for transport in the bloodstream. They are specifically designed for gas exchange. White blood cells (B) are part of the immune system and fight infections. Platelets (C) are responsible for blood clotting. Hematocrit (D) refers to the proportion of red blood cells in the blood, not a specific type of cell responsible for gas transport.
What is the key immune cell involved in granuloma formation?
- A. Mast cells
- B. Macrophages
- C. Neutrophils
- D. Dendritic cells
Correct Answer: B
Rationale: The correct answer is B: Macrophages. Macrophages are key immune cells involved in granuloma formation. They play a crucial role in engulfing and processing pathogens or foreign particles, leading to the formation of granulomas as part of the body's immune response. Mast cells (A) are primarily involved in allergic reactions. Neutrophils (C) are important in the initial immune response to infections but are not typically associated with granuloma formation. Dendritic cells (D) are important in antigen presentation and activation of T cells, but they are not the primary immune cells involved in granuloma formation.
A cell type capable of killing virus-infected cells that provides early protection against viral infection is
- A. Eosinophils
- B. NK cells
- C. Neutrophils
- D. Mast cells
Correct Answer: B
Rationale: The correct answer is B: NK cells. NK cells are part of the innate immune system and can directly kill virus-infected cells, providing early protection against viral infections. They do not require prior exposure to the virus to initiate their killing mechanism, making them crucial for early defense. Eosinophils (A), Neutrophils (C), and Mast cells (D) are not primarily involved in killing virus-infected cells. Eosinophils are more associated with parasitic infections, Neutrophils are primarily involved in bacterial infections, and Mast cells are involved in allergic reactions.
A patient in Russell traction with a Pearson attachment for a fracture of the tibia complains of intense pain at the fracture site. The nurse assesses a temperature of 102° F and increased swelling at the fracture site. Which complication do these findings suggest?
- A. Osteomyelitis
- B. Fat embolism
- C. Traction misalignment
- D. Nonunion of the fracture
Correct Answer: A
Rationale: The correct answer is A: Osteomyelitis. The combination of intense pain, increased swelling, elevated temperature, and presence of traction indicates an infection in the bone, suggesting osteomyelitis. This serious complication requires prompt treatment with antibiotics.
Incorrect choices:
B: Fat embolism - This typically presents with respiratory distress, petechiae, and neurological changes, not with localized pain and swelling.
C: Traction misalignment - This would cause a change in the alignment of the fracture but would not typically present with fever and localized signs of infection.
D: Nonunion of the fracture - Nonunion is a failure of the bone to heal, which would not typically present with the acute signs of infection seen in this case.
Which factors will assist a patient in coping positively with having cancer (select all that apply)?
- A. Feeling of control
- B. Strong support system
- C. Internalization of feelings
- D. Possibility of cure or control
Correct Answer: B
Rationale: Factors such as feeling in control, having a strong support system, and the possibility of cure or control enhance positive coping with cancer.