Endocrine System Questions and Answers PDF Related

Review Endocrine System Questions and Answers PDF related questions and content

At the skeletal muscle sarcomere, Ca2+ ions do each of the following, except:

  • A. Bind to troponin to help uncover tropomyosin
  • B. Help expose active sites on actin strands
  • C. Is stored in the sarcoplasmic reticulum at terminal cisternae
  • D. Helps break the ATP into ADP + inorganic phosphate readying the myosin head to bind another active site
Correct Answer: d

Rationale: Rationale for Correct Answer (D):
1. Ca2+ ions do not directly break down ATP into ADP + inorganic phosphate at the sarcomere.
2. This breakdown occurs through the enzymatic action of myosin ATPase.
3. Ca2+ ions primarily bind to troponin to initiate muscle contraction by moving tropomyosin.
4. Ca2+ ions help expose active sites on actin, facilitating cross-bridge formation.

Summary of Incorrect Choices:
A. Correct - Ca2+ binds to troponin to move tropomyosin, not to uncover it.
B. Correct - Ca2+ aids in exposing active sites on actin, not troponin.
C. Correct - Ca2+ is stored in the sarcoplasmic reticulum, but it is released into the cytoplasm to trigger muscle contraction, not stored in the terminal cisternae.