Wongs Essentials of Pediatric Nursing 11th Edition Test Bank Related

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Autoimmunity is defined as a phenomenon involving which of the following?

  • A. Production of endotoxins that destroy B
  • B. Overproduction of reagin antibody
  • C. Depression of the immune response
  • D. Inability to differentiate self from nonself
Correct Answer: D

Rationale: Autoimmunity is a phenomenon in which the immune system mistakenly targets and attacks the body's own cells, tissues, and organs. This occurs due to a breakdown in the immune system's ability to differentiate "self" from "nonself." In a healthy immune system, immune cells recognize and destroy foreign invaders while avoiding attacking the body's own cells. When this self-tolerance is lost, autoimmune diseases can develop, leading to inflammation, tissue damage, and various health problems. Therefore, autoimmunity is defined by the immune system's inability to distinguish between self and nonself.