Causes of a discrete osteolytic bone lesion in a two-year-old include:
- A. Rickets
- B. Non-accidental injury
- C. Eosinophilic granuloma
- D. Acute lymphoblastic leukaemia
Correct Answer: C
Rationale: Eosinophilic granuloma is a benign bone lesion that can present with osteolytic lesions, typically seen in children as part of Langerhans cell histiocytosis.
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In neonates with anomalous total pulmonary venous return and obstruction, the chest x-ray demonstrates
- A. heart enlarged
- B. prominent pulmonary artery
- C. prominent right ventricle
- D. prominent subaortic stenosis
Correct Answer: D
Rationale: Prominent subaortic stenosis is not typically seen in TAPVR.
Nystagmus can be a presenting sign in:
- A. Partial albinism
- B. Retinopathy of prematurity
- C. Acute vestibulitis
- D. Medulloblastoma
Correct Answer: D
Rationale: Medulloblastoma, a type of brain tumor, can present with nystagmus due to its impact on the cerebellum and brainstem.
The following are transmitted as autosomal dominant traits:
- A. Congenital spherocytosis
- B. Vitamin D-resistant rickets
- C. CAH
- D. Hereditary haemorrhagic telangiectasia
Correct Answer: D
Rationale: Hereditary haemorrhagic telangiectasia is an autosomal dominant disorder. Congenital spherocytosis and Vitamin D-resistant rickets can also be autosomal dominant, but CAH (Congenital Adrenal Hyperplasia) is typically autosomal recessive.
Which client has the highest risk for developing skin cancer?
- A. A 16-year old dark-skinned female who tans in tanning beds once a week
- B. A 65 year-old fair-skinned male who is a construction worker
- C. A 25 year-old dark-skinned male whose mother had skin cancer
- D. A 70 year-old fair-skinned female who works as a secretary
Correct Answer: B
Rationale: Fair-skinned individuals with prolonged sun exposure, such as construction workers, are at higher risk for skin cancer.
Which of the following antibodies has least association with neonatal lupus?
- A. Anti-Ro (SSA)
- B. Anti-La (SSB)
- C. Anti-RNP
- D. Anti-CCP
Correct Answer: D
Rationale: Anti-CCP antibodies have the least association with neonatal lupus compared to the other antibodies listed.
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