Chemically an antigen may be:
- A. Lipid
- B. Protein
- C. Polysaccharide
- D. Any of these
Correct Answer: D
Rationale: The correct answer is D because antigens can be composed of lipids, proteins, or polysaccharides. Antigens are molecules that can elicit an immune response in the body. They can be diverse in their chemical composition, leading to the recognition and response by the immune system. Therefore, the correct choice is D as antigens can be any of these chemical components. Choices A, B, and C are incorrect because they each represent a possible chemical composition of antigens, but the flexibility of antigens to be made up of any of these components makes D the most accurate choice.
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Which of the following is a key feature of Mycobacterium tuberculosis?
- A. Produces spores
- B. Gram-negative
- C. Acid-fast cell wall
- D. Produces toxins
Correct Answer: C
Rationale: The correct answer is C: Acid-fast cell wall. Mycobacterium tuberculosis is characterized by its unique cell wall composition, containing high levels of mycolic acids which make it acid-fast. This property allows it to resist decolorization during acid-fast staining procedures. This distinguishes it from other bacteria.
A: Producing spores is not a key feature of Mycobacterium tuberculosis. Spore formation is more commonly associated with bacterial species such as Bacillus and Clostridium.
B: Mycobacterium tuberculosis is not Gram-negative. It is classified as acid-fast Gram-positive.
D: Mycobacterium tuberculosis does not produce toxins as a key feature. Its pathogenicity is more closely related to its ability to evade host immune responses and persist in host tissues.
4 days after a patient received a gunshot wound of the middle third of the thigh soft tissues his condition suddenly began deteriorating. There are complaints of bursting pain in the wound; pain increases during the last 12 hours. Edema of skin and hypodermic tissue quickly grows. Body temperature is 38,2oC, heart rate is 102/min. The wound edges gape, are dull in color; the muscles, viable as of day before, now protrude into the wound, look boiled, are dull in color, have dirty-grey coating and fall apart when being held with forceps. What infection has developed in the wound?
- A. Anaerobic
- B. Aerobic gram-negative
- C. Putrid
- D. Aerobic gram-positive
Correct Answer: A
Rationale: The correct answer is A: Anaerobic infection. The sudden deterioration, bursting pain, edema, foul appearance of wound, and presence of gas are indicative of gas gangrene caused by anaerobic bacteria like Clostridium perfringens. These bacteria thrive in low oxygen environments, such as deep wound tissues. The symptoms align with the classic presentation of gas gangrene, necessitating immediate surgical intervention.
Choice B: Aerobic gram-negative, is incorrect because anaerobic bacteria, not aerobic gram-negative bacteria, are responsible for gas gangrene.
Choice C: Putrid, is incorrect as it is a general term referring to foul-smelling decay and does not specify the type of infection.
Choice D: Aerobic gram-positive, is incorrect as gas gangrene is typically caused by anaerobic bacteria, not aerobic gram-positive bacteria.
A 16-year-old boy from the rural area entered the technical school. During a regular Mantoux test, it turned out that this boy had a negative reaction. What tactics should the doctor choose as the most rational in this case?
- A. Repeat the test in a month
- B. Serodiagnosis of tuberculosis
- C. Urgent isolation of the boy from his groupmates
- D. BCG vaccination
Correct Answer: D
Rationale: The correct answer is D: BCG vaccination. BCG vaccination is recommended for individuals with a negative Mantoux test result, especially in countries where tuberculosis is prevalent. This vaccination can help provide protection against tuberculosis.
Choice A is incorrect because repeating the Mantoux test in a month is unnecessary since the boy already had a negative reaction.
Choice B is incorrect as serodiagnosis of tuberculosis is not the first-line approach for diagnosis, especially in this scenario.
Choice C is incorrect because urgent isolation is not necessary based solely on the Mantoux test result. Isolation is typically reserved for individuals with active tuberculosis.
Which one of all the clostridia that are associated with the disease myonecrosis/gas-gangrene can produce enterotoxin and could be responsible for the development of food intoxications:
- A. Clostridium septicum
- B. Clostridium perfringens
- C. Clostridium histolyticum
- D. Clostridium novyi (oedemmateins)
Correct Answer: B
Rationale: The correct answer is B: Clostridium perfringens. This bacterium is associated with myonecrosis/gas gangrene and can produce enterotoxin causing food intoxication. Clostridium septicum (A) is associated with wound infections but not known for food intoxications. Clostridium histolyticum (C) is not typically associated with myonecrosis or food intoxications. Clostridium novyi (D) is known for causing black disease in sheep and cattle, not food intoxications.
What is the primary function of bacterial ribosomes?
- A. Synthesize proteins
- B. Generate ATP
- C. Produce DNA
- D. Synthesize lipids
Correct Answer: A
Rationale: The correct answer is A: Synthesize proteins. Bacterial ribosomes are responsible for translating mRNA into proteins through a process called translation. Ribosomes do not generate ATP (choice B), produce DNA (choice C), or synthesize lipids (choice D). These processes are carried out by other cellular components such as mitochondria for ATP production, DNA polymerase for DNA replication, and enzymes for lipid synthesis. The primary function of bacterial ribosomes is protein synthesis, making choice A the correct answer.