Nokea
Children with high-risk neuroblastoma have poor survival. Current treatment consists of all the following EXCEPT
- A. surgery
- B. intensive chemotherapy
- C. radiation
- D. allogenic bone marrow transplantation
Correct Answer: E
Rationale: Differentiating agents like 13-cis-retinoic acid are used instead of allogenic bone marrow transplantation in high-risk neuroblastoma.
You may also like to solve these questions
A 5 months child is brought for routine care. During auscultation of heart you find a short systolic murmur at left upper sternal border with soft 2nd heart sound. The most likely diagnosis is?
- A. Ventricular septal defect
- B. Atrial septal defect
- C. Patent ductus arteriosus
- D. Pulmonary stenosis
Correct Answer: B
Rationale: Atrial septal defect (ASD) often presents with a systolic ejection murmur at the left upper sternal border and a fixed split second heart sound.
You are examining an infant with multiple cutaneous hemangiomas; you suspect involvement of internal organs. The MOST common site of visceral involvement by hemangiomas is
- A. brain
- B. heart
- C. lung
- D. liver
Correct Answer: D
Rationale: Liver is the most common site of visceral involvement by hemangiomas.
The laboratory results of a patient with disseminated intravascular coagulation are likely to include:
- A. decreased levels of fibrin split products.
- B. increased levels of fibrinogen.
- C. increased platelet counts.
- D. prolonged prothrombin and partial thromboplastin times.
Correct Answer: D
Rationale: DIC leads to prolonged clotting times due to consumption of clotting factors and platelets.
Miss OB's malignant tumor in her left breast was discovered to be spreading all over the surrounding and adjacent tissue and not entering the blood stream, it would be:
- A. Malignant
- B. Non-malignant
- C. Benign
- D. B and C
Correct Answer: C
Rationale: A malignant tumor is characterized by its ability to spread to surrounding tissues and potentially enter the bloodstream to form secondary tumors in distant organs (metastasis). In the scenario provided, the tumor in Miss OB's left breast is described as spreading all over the surrounding and adjacent tissue but specifically noted not to be entering the bloodstream. This behavior is more indicative of a benign tumor that is growing locally but is not capable of metastasis. Therefore, the tumor is best classified as benign in this case.
which of the following is a characteristic in a child with acute lymphocytic leukemia?
- A. fatigability
- B. persistent fever of unknown cause
- C. tendency to bruise easily
- D. all of the above are correct
Correct Answer: D
Rationale: Children with acute lymphocytic leukemia commonly present with a combination of symptoms which can include fatigability, persistent fever of unknown cause, and a tendency to bruise easily. Fatigue is a common complaint in children with leukemia due to anemia caused by decreased production of healthy red blood cells. Persistent fevers can be a sign of infection, anemia, or other complications related to leukemia. Additionally, children with leukemia may have a low platelet count, leading to easy bruising or bleeding tendencies. Therefore, all of the characteristics mentioned in the options are correct for a child with acute lymphocytic leukemia.