Choose a drug that is used for both non-Hodgkin's lymphoma and rheumatoid arthritis:
- A. Doxorubicin
- B. Vincristine
- C. Infliximab
- D. Rituximab
Correct Answer: D
Rationale: Rituximab targets CD20 in lymphoma and is also used in rheumatoid arthritis.
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A nurse is ordered to infuse 1,500 mL of IV fluid over 12 hours using a drop factor of 15 gtt/mL. What is the flow rate in drops per minute?
- A. 31.25 gtt/min
- B. 33.33 gtt/min
- C. 41.67 gtt/min
- D. 62.5 gtt/min
Correct Answer: A
Rationale: Flow rate = (1,500 mL 15 gtt/mL) ÷ (12 60) = 22,500 ÷ 720 = 31.25 gtt/min, exactly matching option A.
There is enough preliminary evidence to recommend that children with autism receive which supplemental nutrient?
- A. Vitamin B1 (thiamine)
- B. Vitamin B2 (riboflavin)
- C. Calcium
- D. Omega-3 fatty acids
Correct Answer: D
Rationale: Preliminary evidence suggests omega-3 fatty acids may benefit children with autism.
The nurse is talking with a group of nursing students who are doing clinical hours on the unit. A student asks if all intramuscular (IM) drugs are absorbed the same. What factor would the floor nurse tell the students to affect absorption of the IM administration of drugs?
- A. Perfusion of blood to the subcutaneous tissue
- B. Integrity of the mucous membranes
- C. Environmental temperature
- D. Blood flow to the gastrointestinal tract
Correct Answer: C
Rationale: A cold environmental temperature can cause blood vessels to vasoconstrict and decreases absorption or in a hot environment vasodilate and increase absorption of IM medications. Blood flow to the subcutaneous tissues interferes with subcutaneous injection and blood flow to the gastrointestinal (GI) tract causes alterations in absorption for oral medications. The condition of mucous membranes can interfere with sublingual (under the tongue) and buccal (in the cheek) administration of drugs.
Which of the following is considered a unit dose system?
- A. Floor stock bottle of aspirin 81 mg
- B. A prefilled Lovenox syringe
- C. One cartoon of Phenergan suppository
- D. Floor stock bottle of ibuprofen suspension
Correct Answer: B
Rationale: Examples of unit dose medications include a package that contains one tablet or capsule, a premeasured amount of a liquid drug, a prefilled syringe, or one suppository.
While administering a medication that the nurse has researched and found to have limited effectiveness, the patient tells the nurse, I have read all about this drug and it is such a wonder drug. I'm so lucky my doctor prescribed it because I just know it will treat my problem. The nurse suspects this drug will be more effective than usual for this patient because of what effect?
- A. Cumulative effect
- B. First-pass effect
- C. Placebo effect
- D. Cross-tolerance effect
Correct Answer: C
Rationale: A drug is more likely to be effective if the patient thinks it will work than if the patient believes it will not work. This is called the placebo effect. If a drug is taken in successive doses at intervals that are shorter than recommended, or if the body is unable to eliminate a drug properly, the drug can accumulate in the body, leading to toxic levels and adverse effects. This is a cumulative effect. First-pass effect addresses the reduction of available drug when taken orally due to metabolism in the liver before the drug reaches the bloodstream. Cross-tolerance is resistance to drugs within the same class.