Nokea
Complications of long-term TPN administration are:
- A. Selenium deficiency
- B. Abnormal liver function tests
- C. Osteopaenia
- D. Renal failure
Correct Answer: A
Rationale: Selenium deficiency is a known complication of long-term total parenteral nutrition (TPN) due to inadequate trace element supplementation.
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Causes for hypertension in childhood
- A. PDA
- B. Hemolytic uremic syndrome
- C. Guillain-Barre syndrome
- D. Lead poisoning
Correct Answer: A
Rationale: Patent ductus arteriosus (PDA) is a common cause of hypertension in childhood.
Complement system:
- A. Is activated by bacterial endotoxins by the classical pathway
- B. Reduced C3 and C4 are usual findings in acute glomerulonephritis
- C. Hereditary angioneurotic oedema is caused by deficiency of one of the components of the classical pathway of the system
- D. Is part of humoral immunity
Correct Answer: D
Rationale: The complement system is a key component of humoral immunity, playing a role in the immune response to pathogens.
Causes of hypogonadotropic hypogonadism are:
- A. Kallman's syndrome
- B. Testicular atrophy
- C. Klinefelter's syndrome
- D. Hypothalamic tumour
Correct Answer: A
Rationale: The correct answer is A because Kallman's syndrome is a well-known cause of hypogonadotropic hypogonadism. The other options (b-e) are either causes of hypergonadotropic hypogonadism or unrelated conditions.
Rocker bottom feet and polyvalvular dysplasia are characteristic of which of the following?
- A. Trisomy 19
- B. Trisomy 18
- C. Trisomy 13
- D. Trisomy 21
Correct Answer: B
Rationale: Rocker bottom feet and polyvalvular dysplasia are classic signs of trisomy 18 (Edwards syndrome), a condition that involves multiple congenital anomalies.
Which of the following is an example of ductus dependent systemic circulation?
- A. Severe Ebstein's anomaly
- B. Pulmonary atresia
- C. Tricuspid atresia
- D. Interruption of aortic arch
Correct Answer: D
Rationale: Interruption of aortic arch is ductus dependent as it relies on the ductus arteriosus for systemic blood flow.