Concerning insulin-dependent diabetes mellitus in children:
- A. Microangiopathic changes are rare before puberty
- B. Isophane is shorter acting than soluble insulin
- C. Lipohypertrophy is more common than lipo-atrophy
- D. Fructosamine can be used to monitor glucose control
Correct Answer: A
Rationale: Microangiopathic changes are indeed rare before puberty in children with insulin-dependent diabetes mellitus. Isophane is not shorter acting than soluble insulin, and fructosamine is used to monitor glucose control.
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In statistical methodology:
- A. The median and mean are different when the population distribution is skewed
- B. Mode refers to the value that occurs with the highest frequency
- C. The value of 'r' (coefficient of variation) ranges from -1 to +1
- D. Incidence is defined as the number of cases seen in the population at any given period of time
Correct Answer: A
Rationale: The median and mean differ in skewed distributions because the mean is influenced by extreme values, while the median is not.
Clinical diagnostic clues in an adolescent female with chronic cough:
- A. Pale stools and diarrhoea
- B. Aspergillus precipitin positive
- C. Calcified bronchopulmonary lymph nodes
- D. Whooping cough in the past
Correct Answer: B
Rationale: Aspergillus precipitin positive: A positive Aspergillus precipitin test indicates Aspergillus exposure, which could lead to chronic pulmonary issues, especially in immunocompromised individuals.
In childhood asthma:
- A. Over 90% of patients show exercise-induced bronchoconstriction
- B. Hypercapnia is the first physiological disturbance in status asthmaticus
- C. Infants are unresponsive to bronchodilators
- D. Spontaneous cure occurs before adolescence
Correct Answer: D
Rationale: Spontaneous cure before adolescence is a recognized phenomenon in childhood asthma, though not all cases resolve. Other options are incorrect: exercise-induced bronchoconstriction is common but not universal, hypercapnia occurs late in status asthmaticus, and infants do respond to bronchodilators.
The child becomes unresponsive. The most likely underlying lesion is
- A. cardiomyopathy
- B. anomalous coronary artery
- C. tetralogy of Fallot
- D. constipation
Correct Answer: C
Rationale: Tetralogy of Fallot can cause hypoxic spells leading to unresponsiveness.
During a well baby examination of a 6-week-old infant, poor weight gain, acrocyanosis of the hands and feet, and a respiratory rate of 60 breaths per minute are noted. Oxygen saturation on room air is 93%. What is the correct action?
- A. Follow-up in 1 week to assess the infant's weight.
- B. Order a chest radiograph and an electrocardiogram.
- C. Reassure the parents that the exam is within normal limits.
- D. Refer the infant to a pediatric cardiologist.
Correct Answer: D
Rationale: Infants with oxygen saturation less than 95% and those with poor feeding should be referred emergently to a cardiologist.
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