Nokea
Decongestants such as pseudoephedrine (Sudafed):
- A. Are Schedule III drugs in all states
- B. Should not be prescribed or recommended for children under 4 years of age
- C. Are effective in treating the congestion children experience with the common cold
- D. May cause drowsiness in patients of all ages
Correct Answer: B
Rationale: Pseudoephedrine is unsafe for children under 4 due to serious side effects; it's not Schedule III , variably effective in kids , or typically sedating .
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A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the probability that none of the five patients experience side effects?
- A. 0.8687
- B. 0.1313
- C. 0.00847
- D. 0.0003
Correct Answer: A
Rationale: Using the binomial distribution with n=5, p=0.03, and q=0.97, the probability of zero side effects is calculated as P(X=0) = (5 choose 0) * 0.97^5 = 0.8687, as shown in the document.
Binding of drugs to albumin is irreversible.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: False; binding to albumin is reversible, allowing drugs to dissociate and become active or available for elimination.
A 60-year-old man with Type 2 diabetes mellitus is treated with pioglitazone. Which of the following phrases summarizes best this drug's main mechanism of action?
- A. Blocks intestinal carbohydrate absorption
- B. Causes glycosuria (increased renal glucose excretion)
- C. Increases hepatic gluconeogenesis
- D. Increases target tissue sensitivity to insulin
Correct Answer: D
Rationale: Pioglitazone enhances insulin sensitivity in target tissues like muscle and fat via PPAR-gamma activation.
The patient asks the nurse, Is it safe to take over-the-counter (OTC) medications with prescription medications? What is the nurse's best response?(Select one that does not apply.)
- A. OTC medications can interact with prescription medications.
- B. It is important to tell your doctor all medications you take, including OTC.
- C. OTC medications could mask or hide signs and symptoms of a disease.
- D. You should avoid taking any OTC medication when taking prescription drugs.
Correct Answer: D
Rationale: OTC medications can interact with prescription medications or other OTC so it is always important to consult your pharmacist and provider for advice. To provide the most accurate instruction, the health care provider must know all medications taken including dietary supplements, OTC, and prescription. OTC medications could mask or hide symptoms of a disease so it is always important to consult a physician if symptoms persist. OTC medications are not prohibited when taking prescription drugs as long as no drug interaction occurs. How an OTC will impact a prescription medication varies depending on the medications involved, so it is incorrect to say it will make the prescription drug more effective.
Immunomodulators such as azathioprine may cause a delayed adverse drug reaction known as a type D reaction because they are known:
- A. Teratogens
- B. Carcinogens
- C. To cause hypersensitivity reactions
- D. Hypothalamus-pituitary-adrenal axis suppressants
Correct Answer: B
Rationale: Azathioprine's Type D (delayed) ADRs, like cancer risk , emerge long-term, unlike teratogenicity , hypersensitivity , or HPA suppression .