Despite the use of antibiotic agents, mortality remains high, in the range of 20-25%. Serious morbidity occurs in 50-60% of children with documented infective endocarditis. Of the following, the MOST common morbidity is
- A. heart failure
- B. pulmonary emboli
- C. mycotic aneurysms
- D. acquired ventricular septal defect
Correct Answer: A
Rationale: Heart failure is the most common morbidity in children with infective endocarditis.
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Bronchoconstriction is a recognised side effect of:
- A. Captopril
- B. Salbutamol
- C. Ibuprofen
- D. Paracetamol
Correct Answer: B
Rationale: Salbutamol can cause bronchoconstriction in some cases due to its paradoxical effect, especially if overused or misused.
A 1-day-old is noted to be cyanotic. Physical examination reveals a grade 2-3/6 systolic murmur and a single loud second heart sound. The chest radiograph reveals a normal-sized heart and decreased pulmonary vascular markings. The electrocardiogram (ECG) reveals left ventricular dominance. The next step in the management of this neonate is to administer
- A. sodium bicarbonate
- B. morphine
- C. prostaglandin E1
- D. digoxin
Correct Answer: C
Rationale: Prostaglandin E1 helps maintain ductal patency, which can improve circulation in conditions like transposition of the great arteries or other congenital heart defects causing cyanosis.
The MOST common early long-term complication for those patients who underwent repair of complete atrioventricular canal before the development of pulmonary vascular disease is
- A. left AV valve regurgitation
- B. subaortic stenosis
- C. residual ventricular level shunts
- D. complete heart block
Correct Answer: A
Rationale: Left AV valve regurgitation is a common complication after complete atrioventricular canal repair.
Neurodegenerative diseases include the following:
- A. Niemann-Pick disease
- B. Metachromatic leukodystrophy
- C. Leigh's encephalopathy
- D. Canavan disease
Correct Answer: A
Rationale: The correct answer is A because Niemann-Pick disease is a neurodegenerative disorder. The other options (b-e) are also neurodegenerative diseases.
The aminoacid used in the treatment of hyperammonemia due to certain urea cycle disorders is
- A. Leucine
- B. Valine
- C. Arginine
- D. Isoleucine
Correct Answer: C
Rationale: Arginine is used in the treatment of hyperammonemia due to urea cycle disorders, as it helps in the detoxification of ammonia.