Drugs significantly affected by enzyme induction include the following except:
- A. Barbiturate
- B. Chlorpromazine
- C. Diphenyl hydantoin
- D. Warfarin
Correct Answer: B
Rationale: Barbiturates, phenytoin (diphenyl hydantoin), and warfarin are affected by enzyme induction; chlorpromazine is less so.
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Which of the following beta-blockers also has additional alpha-blocking activity?
- A. Nadolol
- B. Pindolol
- C. Labetalol
- D. Esmolol
Correct Answer: C
Rationale: Labetalol has both beta and alpha-1 blocking activity, making it unique among beta-blockers.
Patients prescribed aspirin therapy require education regarding the signs of aspirin toxicity. An early sign of aspirin toxicity is:
- A. Black tarry stools
- B. Vomiting
- C. Tremors
- D. Tinnitus
Correct Answer: D
Rationale: Tinnitus is an early aspirin toxicity sign; black stools or vomiting are later.
The client has a PRN prescription for ondansetron (Zofran). For which condition should this medication be administered to the postoperative client?
- A. Paralytic ileus
- B. Incisional pain
- C. Urinary retention
- D. Nausea and vomiting
Correct Answer: D
Rationale: Ondansetron is an antiemetic used to treat postoperative nausea and vomiting, as well as nausea and vomiting associated with chemotherapy. The other options are incorrect.
What medication is most likely to cause his weight gain?
- A. Acarbose
- B. Exenatide
- C. Glyburide
- D. Pioglitazone
Correct Answer: D
Rationale: Pioglitazone is most likely to cause weight gain due to fluid retention and fat accumulation.
A nurse is reviewing a client's health record and notes that the client experiences permanent extrapyramidal effects caused by a previous medication. The nurse should recognize that the medication affected which of the following systems in the client?
- A. Cardiovascular
- B. Immune
- C. Central nervous
- D. Gastrointestinal
Correct Answer: C
Rationale: Extrapyramidal effects are movement disorders caused by medications affecting the central nervous system , like antipsychotics.
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