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Drugs that are prone to cause adverse drug effects include:
- A. Diuretics
- B. Inhaled anticholinergics
- C. Insulins
- D. Stimulants
Correct Answer: D
Rationale: Stimulants frequently cause ADRs (e.g., tachycardia), though diuretics and insulins also have risks; anticholinergics are less broad.
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The nurse explains that what drug resource book is compiled from package inserts?
- A. Nurse's Drug Guide
- B. Physicians Desk Reference (PDR)
- C. Drug Facts and Comparisons
- D. AMA Drug Evaluations
Correct Answer: B
Rationale: The PDR is a compilation of information found on package inserts. The Nurse's Drug Guide uses more easily understood language and incorporates nursing considerations and patient teaching points. Drug Facts and Comparisons includes cost comparison, often not found in other drug resource guides. The AMA Drug Evaluations is far less biased than the PDR and includes drugs still in the research stage of development.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh between 60 kg and 75 kg.
- A. 450
- B. 476
- C. 480
- D. 490
Correct Answer: B
Rationale: Convert to z-scores: (60-70)/3 = -3.33, (75-70)/3 = 1.67. P(-3.33 < Z ≤ 1.67) = P(Z ≤ 1.67) - P(Z ≤ -3.33) = 0.9525 - (1 - 0.9996) = 0.9521. Then, 0.9521 * 500 ≈ 476, as per the document.
Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secretions. Each replacement drug has lipase, protease, and amylase components, but the drug is prescribed in units of:
- A. Lipase
- B. Protease
- C. Amylase
- D. Pancreatin
Correct Answer: A
Rationale: Pancreatic enzymes are dosed by lipase units, targeting fat malabsorption in cystic fibrosis.
The first-line treatment for cough related to an upper respiratory tract infection (URI) in a 5-year-old child is:
- A. Fluids and symptomatic care
- B. Dextromethorphan and guaifenesin syrup (Robitussin DM for Kids)
- C. Guaifenesin and codeine syrup (Tussin AC)
- D. Chlorpheniramine and dextromethorphan syrup (Nyquil for Kids)
Correct Answer: A
Rationale: Fluids and symptomatic care are safest and recommended for URI cough in young children; cough suppressants are discouraged under 6.
Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by:
- A. Increasing heart rate to improve cardiac output
- B. Reducing vascular smooth muscle tone
- C. Increasing aldosterone-mediated volume activity
- D. Reducing aqueous humor production
Correct Answer: B
Rationale: Beta blockers like atenolol reduce vascular tone and heart rate, lowering blood pressure.