Nokea
Which of the following statements about aminoglycosides is false?
- A. They have short half-lives
- B. They are bactericidal
- C. They exacerbate weakness in myasthenia gravis patients
- D. None of the Above
Correct Answer: D
Rationale: All statements are true: aminoglycosides have short half-lives (2-3 hours), are bactericidal, and can worsen myasthenia gravis by neuromuscular blockade.
You may also like to solve these questions
A 68-year-old patient who must take antihistamines for severe allergies is planning a vacation to Mexico. The nurse will encourage the patient to:
- A. Avoid sightseeing during the hottest part of the day
- B. Discontinue the antihistamines if he becomes extremely restless
- C. Decrease the dosage of the drugs if he experiences excessive thirst
- D. Continue taking the antihistamines even if he begins to hallucinate
Correct Answer: A
Rationale: Antihistamines can decrease sweating by blocking cholinergic receptors, placing the patient at high risk for heat stroke. Avoiding the hottest part of the day will help prevent dehydration and heat prostration. Extreme restlessness could indicate Parkinson-like syndrome not usually associated with antihistamines. Excessive thirst is characteristic of hyperglycemia, and hallucinations are associated with drugs that affect neurologic functioning. Nurses should never tell patients to decrease or discontinue a drug unless the prescriber has instructed them to do so.
Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secretions. Each replacement drug has lipase, protease, and amylase components, but the drug is prescribed in units of:
- A. Lipase
- B. Protease
- C. Amylase
- D. Pancreatin
Correct Answer: A
Rationale: Pancreatic enzymes are dosed by lipase units, targeting fat malabsorption in cystic fibrosis.
After teaching a group of nursing students about the half-life of a drug, the instructor determines the need for additional teaching when the students identify which of the following as true? Select all that apply:
- A. Half-life can be decreased in clients with renal disease.
- B. Half-life can help determine dosing frequency.
- C. Half-life does not change throughout a client's life.
- D. Liver disease can decrease half-life.
Correct Answer: B
Rationale: Half-life is the measure of the rate at which drugs are removed from the body, and any difficulty in excreting a drug increases half-life, including liver or kidney disease or advanced age. Thus, A and C are incorrect statements requiring further teaching.
Which of the following is true about procainamide and its dosing schedule?
- A. It produces bradycardia and should be used cautiously in patients with cardiac conditions that a slower heart rate might worsen.
- B. Gastrointestinal adverse effects are common so the drug should be taken with food.
- C. Adherence can be improved by using a sustained release formulation that can be given once daily.
- D. Doses of this drug should be taken evenly spaced around the clock to keep an even blood level.
Correct Answer: D
Rationale: Even spacing maintains steady procainamide levels.
The following cholinesterase inhibitor is used in anaesthesia:
- A. Neostigmine
- B. Physostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Neostigmine reverses non-depolarizing neuromuscular blockers in anesthesia.