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You are treating a patient with a diagnosis of Alzheimer's disease. The patient's wife mentions difficulty with transportation to the clinic. Which medication is the best choice?
- A. Donepezil
- B. Tacrine
- C. Doxazosin
- D. Verapamil
Correct Answer: A
Rationale: Donepezil, with once-daily dosing, is practical for patients with transportation issues.
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Drugs that are prone to cause adverse drug effects include:
- A. Diuretics
- B. Inhaled anticholinergics
- C. Insulins
- D. Stimulants
Correct Answer: D
Rationale: Stimulants frequently cause ADRs (e.g., tachycardia), though diuretics and insulins also have risks; anticholinergics are less broad.
A nurse is assessing a client who is taking Digoxin to treat heart failure. Which of the following findings is a manifestation of digoxin toxicity?
- A. Bruising
- B. Report of metallic taste
- C. Muscle pain
- D. Report of anorexia
Correct Answer: D
Rationale: Anorexia is a common early sign of digoxin toxicity.
A pharmacology student asks the instructor what an accurate description of a drug agonist is. What is the instructors best response?
- A. A drug that reacts with a receptor site on a cell preventing a reaction with another chemical on a different receptor site
- B. A drug that interferes with the enzyme systems that act as catalyst for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with some receptor sites preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
The nurse is teaching a patient who will be discharged home with naltrexone (ReVia) after treatment for opioid addiction. What information will the nurse include in the teaching for this patient?
- A. This drug will help control cravings
- B. You may take this drug once weekly
- C. ReVia blocks the pleasurable effects of opioids
- D. If you discontinue this drug abruptly, you will have withdrawal symptoms
Correct Answer: C
Rationale: Naltrexone blocks opioid euphoria; it doesn't reduce cravings or cause withdrawal on stop . ReVia acts by blocking the pleasurable effects of opioids.
When administering a prescribed drug to a client, which action would be completely inappropriate? (Select one that does not apply.)
- A. Charting immediately on the MAR after drug administration
- B. Removing a drug from an unlabeled container
- C. Giving a drug that someone else prepared
- D. Crushing tablets or opening capsules
Correct Answer: A
Rationale: The nurse should always record immediately on the MAR after drug administration. The nurse should never remove a drug from an unlabeled container, give a drug that someone else prepared, or crush tablets or open capsules without consulting a pharmacist. The drug's unit dose wrapper should remain on until the nurse arrives at the client's bedside.