During early tooth development, vitamin A deficiency leads to enamel hypoplasia and defective dentin formation. Because of its effect on soft tissues and bone, vitamin A contributes to normal spacing of teeth.
- A. Both statements are true.
- B. Both statements are false.
- C. The first statement is true; the second is false.
- D. The first statement is false; the second is true.
Correct Answer: A
Rationale: Both statements are true. The effect of vitamin A on the growth of soft tissues and bones naturally extends to the teeth and surrounding structures. Enamel hypoplasia, involving defective enamel matrix and incomplete calcification of enamel and dentin, can be due to vitamin A deficiency. The effect of this vitamin upon surrounding bone directly affects spacing patterns of the teeth within the bone and dentition. Choice A is correct because both statements accurately describe the influence of vitamin A on tooth development. Choices B, C, and D are incorrect as they do not reflect the accuracy of the statements provided.
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Which vitamin acts most like a hormone?
- A. Vitamin A
- B. Vitamin B
- C. Vitamin D
- D. Vitamin C
Correct Answer: C
Rationale: The correct answer is Vitamin D. Although vitamin D, also known as calciferol, has been called a vitamin, it is more appropriately classified as a hormone. Like hormones, vitamin D acts to control the function of other cell types. For example, it helps the body absorb and regulate skeletal calcium and phosphorus levels. Choice A (Vitamin A) plays a crucial role in vision and immune function. Choice B (Vitamin B) is a complex of different vitamins that play various roles in the body. Choice D (Vitamin C) is important for collagen production and acts as an antioxidant.
Wernicke-Korsakoff syndrome is associated with which vitamin deficiency?
- A. Thiamine (B1)
- B. Riboflavin (B2)
- C. Niacin (B3)
- D. Pyridoxine (B6)
Correct Answer: A
Rationale: Wernicke-Korsakoff syndrome is indeed associated with thiamine (vitamin B1) deficiency. This syndrome is commonly seen in individuals with chronic alcoholism due to poor diet and impaired thiamine absorption. Thiamine is essential for normal brain function and energy metabolism. Riboflavin (B2) deficiency can lead to symptoms like sore throat and swollen mucous membranes, not Wernicke-Korsakoff syndrome. Niacin (B3) deficiency causes pellagra, characterized by dermatitis, diarrhea, dementia, and death, but not Wernicke-Korsakoff syndrome. Pyridoxine (B6) deficiency can result in dermatitis, glossitis, and peripheral neuropathy, but it is not associated with Wernicke-Korsakoff syndrome.
Each is a physiologic role of vitamin D, except one. Which is the exception?
- A. Hematopoiesis
- B. Cardiac and neuromuscular function
- C. Immune responses
- D. Serum calcium regulation
Correct Answer: A
Rationale: The correct answer is A, Hematopoiesis. Vitamin D plays a crucial role in regulating serum calcium levels, which is essential for maintaining cardiac and neuromuscular function. Additionally, vitamin D is involved in modulating immune responses. However, hematopoiesis, the formation of red blood cells, is not a direct physiologic role of vitamin D. Therefore, hematopoiesis is the exception among the listed functions of vitamin D.
Inadequate intake of vitamin A occurs in lower socioeconomic groups due to a lack of resources to purchase and consume vegetables and fruits.
- A. Both the statement and the reason are correct and related.
- B. Both the statement and the reason are correct but are not related.
- C. The statement is correct, but the reason is not correct.
- D. The statement is not correct, but the reason is correct.
Correct Answer: A
Rationale: Both the statement and the reason are correct and related. Inadequate intake of vitamin A in lower socioeconomic groups is due to a lack of resources to purchase and consume vegetables and fruits. This is supported by the fact that the average intake in the United States meets the Recommended Dietary Allowance (RDA) for vitamin A intake, except in lower socioeconomic groups. These individuals often lack the financial means to buy, prepare, and eat a variety of fruits and vegetables, leading to deficiencies. It's important to note that because vitamin A can be stored in the liver, most adults have sufficient quantities to maintain health. Choices B, C, and D are incorrect because the statement and reason are both accurate and logically connected, as the lack of resources directly impacts the ability to obtain necessary sources of vitamin A.
How is the equalization of solute concentration of intracellular fluids (ICFs) and extracellular fluids (ECFs accomplished?
- A. Semipermeable membranes.
- B. Hydration.
- C. Osmotic pressure.
- D. Perspiration.
Correct Answer: C
Rationale: The correct answer is C, osmotic pressure. Osmotic pressure within the body equalizes the solute concentration of ICFs and ECFs by shifting small amounts of water in the direction of higher concentration solute. Semipermeable membranes separate one fluid compartment from another and do not directly equalize solute concentrations. Hydration and perspiration are important elements of fluid balance but do not directly achieve the equalization of solute concentrations between ICFs and ECFs, which is primarily regulated by osmotic pressure.
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