Physiological Adaptation NCLEX PN Questions Related

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Elderly persons with pernicious anemia should be instructed:

  • A. to increase their dietary intake of foods high in B12.
  • B. that they do not need to return for follow-up for at least a month after initiation of treatment.
  • C. that oral B12 is safer and less expensive than parenteral replacement.
  • D. that diarrhea can be a transient side effect of B12 injections.
Correct Answer: D

Rationale: Pernicious anemia is a megaloblastic, macrocytic, normochronic anemia caused by a deficiency of the intrinsic factor produced by the stomach. This results in malabsorption of vitamin B12, which is necessary for DNA synthesis and maturation of RBC. Education should include side effects of Vitamin B12, which can include pain and burning at the injection site, peripheral vascular thrombosis, and transient diarrhea.