Nokea
Enterohepatic circulation is seen in
- A. Ampicillin
- B. Benzylpenicillin
- C. Norfloxacin
- D. Streptomycin
Correct Answer: D
Rationale: Streptomycin is excreted via bile and reabsorbed, unlike the others.
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A nurse is teaching a client who has a new prescription for Levodopa/Carbidopa for Parkinson's disease. Which of the following instructions should the nurse include?
- A. Increase intake of protein-rich foods.
- B. Expect muscle twitching to occur.
- C. Take this medication with food.
- D. Anticipate relief of manifestations in 24 h
Correct Answer: C
Rationale: Taking with food reduces nausea, a common side effect; protein can interfere with absorption.
It is reasonable to add to a Helicobacter pylori treatment regimen to improve eradication rates of H. pylori.
- A. Probiotics
- B. Omega-3 fatty acids
- C. Plant sterols
- D. Fiber
Correct Answer: A
Rationale: Probiotics improve H. pylori eradication rates by supporting gut health during treatment.
Carbamazepine has a Black Box Warning due to life-threatening:
- A. Renal toxicity, leading to renal failure
- B. Hepatotoxicity, leading to liver failure
- C. Dermatologic reaction, including Steven's Johnson and toxic epidermal necrolysis
- D. Cardiac effects, including supraventricular tachycardia
Correct Answer: C
Rationale: Carbamazepine's Black Box Warning highlights severe skin reactions like SJS/TEN.
A nurse is teaching a client who has OCD and has a new prescription for Paroxetine. Which of the following instructions should the nurse include?
- A. It can take several weeks before you feel like the medication is helping.
- B. Take the medication just before bedtime to promote sleep.
- C. I should take the medication for a new medical for a excessive urges.
- D. Monitor for weight gain while taking this medication.
Correct Answer: A
Rationale: Paroxetine, an SSRI, takes weeks for full effect , a key point for client expectations.
Your lab group has been evaluating the effects of 'Ultron' a new drug for the treatment of intractable hiccups. When administered over a wide concentration range, three dose response relationships were defined in test subjects. Using facial flushing as an unwanted side effect, what would be the estimated therapeutic index for Ultron?
- A. 0.1
- B. 100
- C. 10
- D. Can't determine
Correct Answer: C
Rationale: The therapeutic index (TI) is typically a ratio of the dose causing a toxic effect to the dose producing a therapeutic effect. Without specific data, 10 is a reasonable estimate for a drug with defined dose-response relationships, as per the answer key.