Etidronate is prescribed for a postmenopausal woman who is at great risk for developing osteoporosis. Which of the following adverse effects to this drug is the patient most likely to experience?
- A. Tetany
- B. Cholelithiasis
- C. Esophagitis
- D. Renal damage from calcium stone formation
Correct Answer: C
Rationale: Bisphosphonates like etidronate commonly cause esophagitis if not taken properly.
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A patient who has a long history of alcohol abuse is admitted to the hospital for detoxification. In addition to medications needed to treat withdrawal symptoms, the nurse will anticipate giving intravenous
- A. dopamine to restore blood pressure
- B. fluid boluses to treat dehydration
- C. glucose to prevent hypoglycemia
- D. thiamine to treat nutritional deficiency
Correct Answer: D
Rationale: Thiamine prevents Wernicke's encephalopathy in alcohol detox; glucose follows if needed. Thiamine should be given to prevent Wernicke's encephalopathy in patients treated for alcoholism.
Following is the example of second generation antihistaminic:
- A. Diphenhydramine
- B. Promethazine
- C. Chlorpheniramine
- D. Cetirizine
Correct Answer: D
Rationale: Cetirizine is a second-generation antihistamine with less sedation due to reduced CNS penetration, unlike first-generation drugs like diphenhydramine, promethazine, and chlorpheniramine.
Larry has heart failure, which is being treated with digoxin because it exhibits:
- A. Negative inotropism
- B. Positive chronotropism
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: D
Rationale: Digoxin has positive inotropic effects, increasing contractility, not negative or chronotropic.
A client asks the NP about the differences in drug effects between men and women. What is known about the differences between the pharmacokinetics of men and women?
- A. Body temperature varies between men and women.
- B. Muscle mass is greater in women.
- C. Percentage of fat differs between genders.
- D. Proven subjective factors exist between the genders.
Correct Answer: C
Rationale: Gender differences in pharmacokinetics are largely due to fat percentage , affecting drug distribution; muscle mass is greater in men (B is false), and temperature/subjective factors are less impactful.
A nurse is providing teaching for a male client who has Schizophrenia and is taking Risperidone. Which of the following instructions should the nurse include in the teaching?
- A. Add extra snacks to your diet to prevent weight loss.
- B. Notify the provider if you develop breast enlargement.
- C. You may begin to have mild seizures while taking this medication.
- D. This medication is likely to increase your libido.
Correct Answer: B
Rationale: Risperidone can cause gynecomastia , a side effect to report; it often decreases libido and causes weight gain.
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