Examples of cyanotic heart disease include:
- A. Ebstein's anomaly
- B. Pulmonary stenosis
- C. Coarctation of aorta
- D. Hypoplastic left heart syndrome
Correct Answer: D
Rationale: Hypoplastic left heart syndrome is a form of cyanotic heart disease. Ebstein's anomaly and pulmonary stenosis can also cause cyanosis, but coarctation of the aorta typically does not.
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The causes of elevated maternal serum AFP are:
- A. Trisomy 21
- B. Exomphalos
- C. Marfan syndrome
- D. Meningomyelocele
Correct Answer: D
Rationale: Elevated maternal serum alpha-fetoprotein (AFP) is associated with neural tube defects such as meningomyelocele, due to leakage of AFP into the amniotic fluid.
The most likely diagnosis in the patient described is
- A. persistent pulmonary hypertension
- B. transposition of the great arteries
- C. truncus arteriosus
- D. pulmonary atresia
Correct Answer: B
Rationale: Transposition of the great arteries often presents with cyanosis due to mixing of oxygenated and deoxygenated blood.
In a patient with painful joint swelling the following investigations are diagnostic:
- A. C-reactive protein
- B. Antinuclear antibodies
- C. Serum C3 (complement) levels
- D. Microscopic examination of synovial fluid
Correct Answer: D
Rationale: Microscopic examination of synovial fluid can reveal crystals, infection, or inflammation, providing a definitive diagnosis.
Patients with a small PDA have the following criteria EXCEPT
- A. asymptomatic risk for endocarditis
- B. normal peripheral pulses
- C. normal pulmonary artery pressure
- D. normal life expectancy
Correct Answer: A
Rationale: Small PDAs typically have a low risk for endocarditis.
Appropriate initial management steps in an acute anaphylactic reaction to a blood transfusion include:
- A. Nebulised steroids
- B. Oxygen
- C. Intravenous hydrocortisone
- D. Intravenous anti-H2 agent
Correct Answer: B
Rationale: Oxygen is a critical initial management step in anaphylaxis to ensure adequate oxygenation during the acute phase.