Nokea
Food in the gastrointestinal tract affects drug absorption by:
- A. Altering the pH of the colon, which decreases absorption
- B. Competing with the drug for plasma proteins
- C. Altering gastric emptying time
- D. Altering the pH of urine
Correct Answer: C
Rationale: Food alters gastric emptying time, which can delay or enhance drug absorption depending on the drug's properties.
You may also like to solve these questions
Twenty-year-old Annie comes to the clinic complaining of copious yellow-green eye discharge. Gram stain indicates she most likely has gonococcal conjunctivitis. While awaiting the culture results, the plan of care should be:
- A. None, wait for the culture results to determine the course of treatment
- B. Ciprofloxacin (Ciloxan) ophthalmic drops
- C. IM ceftriaxone
- D. High-dose oral amoxicillin
Correct Answer: C
Rationale: Gonococcal conjunctivitis requires urgent IM ceftriaxone; waiting risks progression.
Elimination after 4 half lives in first order kinetics is
- A. 84%
- B. 93%
- C. 80.50%
- D. 4.75%
Correct Answer: B
Rationale: After 4 half-lives, 93.75% (1 - 1/16) of the drug is eliminated in first-order kinetics.
Abrupt withdrawal of beta blockers can be life threatening. Patients at highest risk for serious consequences of rapid withdrawal are those with:
- A. Angina
- B. Coronary artery disease
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: C
Rationale: Patients with angina and CAD are at high risk for rebound effects like myocardial infarction.
Immune globulin serums:
- A. Provide active immunity against infectious diseases
- B. Are contraindicated during pregnancy
- C. Are heated to above body temperature to kill most hepatitis, HIV, and other viruses such as parvovirus
- D. Are derived from pooled plasma of adults and contain specific antibodies in proportion to the donor population
Correct Answer: D
Rationale: Immune globulins are passive immunity from pooled plasma; they're not active , not contraindicated in pregnancy , and not heated .
Robert, age 51 years, has been told by his primary care provider (PCP) to take an aspirin a day. Why would this be recommended?
- A. He has arthritis and this will help with the inflammation and pain
- B. Aspirin has anti-platelet activity and prevents clots that cause heart attacks
- C. Aspirin acidifies the urine and he needs this for prostate health
- D. He has a history of GI bleed, and one aspirin a day is a safe dosage
Correct Answer: B
Rationale: Aspirin's antiplatelet effect reduces cardiovascular risk, a common recommendation for men over 50; arthritis or prostate aren't primary reasons.