Nokea
For the structure of rubella virus, it is true that
- A. has icosahedral type of symmetry
- B. is ssDNA virus
- C. does not have an envelope
- D. does not have glycoprotein spikes
Correct Answer: A
Rationale: Step 1: Rubella virus belongs to the Togaviridae family, which typically exhibits icosahedral symmetry.
Step 2: Icosahedral symmetry refers to a structure with 20 equilateral triangular faces, which is characteristic of many viruses, including rubella.
Step 3: Therefore, choice A is correct as rubella virus indeed has icosahedral type of symmetry.
Summary:
- Choice B is incorrect as rubella virus is an ssRNA virus, not ssDNA.
- Choice C is incorrect as rubella virus does have an envelope derived from the host cell membrane.
- Choice D is incorrect as rubella virus does have glycoprotein spikes on its surface.
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A child is ill with diphtheria. A smear of the affected mucous membrane revealed blue rods with thickenings at the poles. What staining method was used?
- A. Neisser
- B. Gram
- C. Ziehl-Neelsen
- D. Loeffler
Correct Answer: A
Rationale: The correct answer is A: Neisser staining method. Neisser staining method is used to stain diphtheria bacilli, which appear as blue rods with thickenings at the poles. The rationale is that Neisser staining specifically targets and highlights the characteristics of the diphtheria bacilli.
Incorrect choices:
B: Gram staining is not specific for diphtheria bacilli and does not show the characteristic blue rods with thickenings at the poles.
C: Ziehl-Neelsen staining is used for acid-fast bacteria like Mycobacterium tuberculosis, not for diphtheria bacilli.
D: Loeffler staining is used for diphtheria bacilli but does not produce blue rods with thickenings at the poles as seen in this case.
Mycoplasma species lack:
- A. Cell wall
- B. Plasma membrane
- C. DNA
- D. Ribosomes
Correct Answer: A
Rationale: The correct answer is A: Cell wall. Mycoplasma species lack a cell wall, making them unique among bacteria. This is because they have a flexible cell membrane that provides structural support instead of a rigid cell wall. The absence of a cell wall allows them to be pleomorphic and gives them resistance to certain antibiotics targeting cell wall synthesis. Plasma membrane (B), DNA (C), and ribosomes (D) are present in Mycoplasma species, so they are not the correct answer.
Which of the following bacteria should be handled in a Biosafety Level 2 facility?
- A. Micrococcus luteus
- B. Bacillus subtilis
- C. Salmonella
- D. Staphylococcus epidermidis
Correct Answer: C
Rationale: The correct answer is C: Salmonella. This bacterium should be handled in a Biosafety Level 2 facility due to its potential to cause disease in humans. Salmonella is a pathogenic bacterium that can cause foodborne illnesses and infections. Handling it in a Biosafety Level 2 facility ensures proper containment and protection of personnel.
A: Micrococcus luteus and B: Bacillus subtilis are common environmental bacteria that do not pose significant risks to human health, so they can be safely handled in lower biosafety levels.
D: Staphylococcus epidermidis is a common skin commensal bacterium that is generally not considered highly pathogenic, so it does not require Biosafety Level 2 containment.
Which of the following best describes the function of bacterial capsules?
- A. Enhance bacterial motility
- B. Enable bacterial adherence to surfaces
- C. Prevent bacterial DNA replication
- D. Protect bacteria from desiccation
Correct Answer: B
Rationale: The correct answer is B: Enable bacterial adherence to surfaces. Bacterial capsules are a protective layer outside the cell wall that helps bacteria adhere to surfaces and evade host immune responses. This allows bacteria to colonize and infect host tissues.
A: Enhancing bacterial motility is typically associated with flagella, not capsules.
C: Bacterial DNA replication is not directly affected by capsules.
D: Bacterial capsules do play a role in protecting bacteria from desiccation by providing a barrier against drying out. However, the primary function is enabling adherence to surfaces.
Which bacteria is responsible for causing cholera?
- A. Shigella dysenteriae
- B. Vibrio cholerae
- C. Salmonella enterica
- D. Clostridium perfringens
Correct Answer: B
Rationale: The correct answer is B: Vibrio cholerae. Cholera is caused by this specific bacterium due to its production of cholera toxin, leading to severe watery diarrhea. Shigella dysenteriae causes dysentery, Salmonella enterica causes salmonellosis, and Clostridium perfringens causes food poisoning, none of which present with the characteristic symptoms of cholera.